Interactor 1: PRS6A (P33297)
26S proteasome regulatory subunit 6A (Tat-binding protein homolog 1) (TBP-1)
Gene: RPT5

Interactor 2: PRS10 (P53549)
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit)
Gene: RPT4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 11283351, 10688190, 22037170, 11742986, 16284124, 18467557, 19243080, 36621624, 37968396, 22615397, 22875988, 22307589, 19446322
Identification Methods two hybrid pooling approach, two hybrid, cross-linking study, affinity chromatography technology, protein complementation assay, anti tag coimmunoprecipitation, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB, AAA_lid_3~AAA_lid_3, Prot_ATP_ID_OB~Prot_ATP_ID_OB
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0016887 - ATP hydrolysis activity
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 434
Sc

1 437
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Rn
+ Af
+ Hs
+ Hs
+ Dm
+ Dm
+ Sc
+ Sc
+ Sc
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024