HitPredict

Interactor 1: SEC3 (P33332)
Exocyst complex component SEC3 (Protein PSL1)
Gene: SEC3

Interactor 2: RHO3 (Q00245)
GTP-binding protein RHO3
Gene: RHO3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20823269
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Sec3-PIP2_bind
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1336 Sc			1 231
+	Sc
		419677 SEC3_YEAST (1-1336): 0: 1233: 100.00		RHO1_YEAST (15-211): 1.23e-64: 201: 49.75
+	Hs
		254433 ROCK2_HUMAN (60-738): 1.7e-25: 117: 10.62		RHOC_HUMAN (15-231): 1.07e-88: 261: 46.08
+	Hs
		925488 MY18A_HUMAN (102-736): 1.57e-29: 130: 10.56		RAC1_HUMAN (17-231): 5.6e-78: 234: 40.00
+	Hs
		545537 MY18A_HUMAN (102-736): 1.57e-29: 130: 10.56		RAC2_HUMAN (17-231): 3.86e-74: 224: 38.61
+	Hs
		900754 MY18A_HUMAN (102-736): 1.57e-29: 130: 10.56		RHOA_HUMAN (18-231): 3.81e-74: 224: 46.26
+	Hs
		892521 MY18A_HUMAN (102-736): 1.57e-29: 130: 10.56		RAC3_HUMAN (17-211): 3.31e-73: 222: 41.54
+	Hs
		254468 ROCK2_HUMAN (60-738): 1.7e-25: 117: 10.62		RAC1_HUMAN (17-231): 5.6e-78: 234: 40.00
+	Hs
		545482 MY18B_HUMAN (335-630): 2.09e-27: 123: 19.56		RAC2_HUMAN (17-231): 3.86e-74: 224: 38.61
+	Dm
		185503 TGO1_DROME (262-466): 1.65e-27: 123: 24.34		O18332_DROME (6-229): 2.49e-73: 223: 23.75
+	Hs
		254464 ROCK2_HUMAN (60-738): 1.7e-25: 117: 10.62		RHOA_HUMAN (18-231): 3.81e-74: 224: 46.26
+	Hs
		254472 ROCK2_HUMAN (60-738): 1.7e-25: 117: 10.62		RHOG_HUMAN (16-231): 1.01e-73: 223: 41.20
+	Hs
		254462 ROCK2_HUMAN (60-738): 1.7e-25: 117: 10.62		RAC3_HUMAN (17-211): 3.31e-73: 222: 41.54
+	Mm
		823530 CTRO_MOUSE (85-616): 1.26e-20: 101: 10.52		RAC1_MOUSE (17-231): 5.6e-78: 234: 40.00
+	Mm
		823539 CTRO_MOUSE (85-616): 1.26e-20: 101: 10.52		RHOA_MOUSE (18-231): 8.93e-75: 226: 46.73
+	Hs
		915875 MY18A_HUMAN (102-736): 1.57e-29: 130: 10.56		RHOB_HUMAN (15-211): 5.46e-61: 191: 49.75
+	Hs
		254467 ROCK2_HUMAN (60-738): 1.7e-25: 117: 10.62		RHOB_HUMAN (15-211): 5.46e-61: 191: 49.75
+	Hs
		120567 MY18A_HUMAN (102-736): 1.57e-29: 130: 10.56		RHOD_HUMAN (18-213): 3.34e-52: 169: 40.82
+	Hs
		876347 AFAD_HUMAN (249-448): 1.84e-22: 107: 26.40		RHOB_HUMAN (15-211): 5.46e-61: 191: 49.75
+	Hs
		254515 ROCK2_HUMAN (60-738): 1.7e-25: 117: 10.62		RHOF_HUMAN (16-213): 8.3e-53: 171: 42.42
+	Hs
		120238 ROCK2_HUMAN (60-738): 1.7e-25: 117: 10.62		RHOD_HUMAN (18-213): 3.34e-52: 169: 40.82