HitPredict

Interactor 1: SLA2 (P33338)
Protein SLA2 (Transmembrane protein MOP2)
Gene: SLA2

Interactor 2: ENT2 (Q05785)
Epsin-2
Gene: ENT2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	29362354, 37968396
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ANTH~ENTH
Common GO terms	GO:0000147 - actin cortical patch assembly GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0007015 - actin filament organization GO:0043332 - mating projection tip
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 968 Sc			1 613
+	Sc
		704813 SLA2_YEAST (1-968): 3.56e-71: 257: 100.00		ENT1_YEAST (1-514): 2.63e-90: 288: 50.97
+	Hs
		255369 HIP1R_HUMAN (3-962): 5.64e-58: 218: 19.98		EPN1_HUMAN (2-542): 1.93e-82: 271: 18.89
+	Hs
		1036403 PICAL_HUMAN (6-348): 1.41e-51: 194: 15.73		EPN4_HUMAN (3-575): 9.26e-84: 276: 16.80
+	Hs
		1036509 PICAL_HUMAN (6-348): 1.41e-51: 194: 15.73		EPN1_HUMAN (2-542): 1.93e-82: 271: 18.89
+	Hs
		124413 HIP1_HUMAN (4-965): 1.95e-61: 229: 19.25		ITSN1_HUMAN (123-593): 6.84e-49: 186: 15.39
+	Hs
		1036409 PICAL_HUMAN (6-348): 1.41e-51: 194: 15.73		ITSN1_HUMAN (123-593): 6.84e-49: 186: 15.39
+	Hs
		522614 MYH7_HUMAN (119-710): 1.06e-14: 81.1: 7.72		EPN4_HUMAN (3-575): 9.26e-84: 276: 16.80
+	Hs
		1057077 MY18A_HUMAN (338-781): 3.03e-11: 70: 14.38		EPN4_HUMAN (3-575): 9.26e-84: 276: 16.80
+	Hs
		149481 CTRO_HUMAN (216-968): 7.93e-72: 263: 14.38		PCLO_HUMAN (163-605): 1.09e-12: 73.9: 10.71
+	Hs
		307529 PICAL_HUMAN (6-348): 1.41e-51: 194: 15.73		EPN2_HUMAN (182-557): 9.06e-16: 82.8: 10.03
+	Dm
		404245 MYSA_DROME (312-961): 6.46e-11: 68.9: 10.11		TITIN_DROME (127-612): 4.03e-26: 116: 11.46