HitPredict

Interactor 1: GRN (P28799)
Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)]
Gene: GRN

Interactor 2: TRI33 (Q9UPN9)
E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)
Gene: TRIM33

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36261009
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 593 Hs			1 1127
+	Hs
		705248 GRN_HUMAN (1-593): 0: 726: 100.00		PML_HUMAN (83-635): 1.12e-60: 226: 16.27
+	Mm
		1222044 Q9D2V3_MOUSE (1-593): 0: 712: 75.04		PML_MOUSE (108-639): 2.98e-59: 222: 16.91
+	Hs
		623121 GRN_HUMAN (1-593): 0: 726: 100.00		RO52_HUMAN (213-594): 3.86e-56: 204: 13.65
+	Hs
		705544 GRN_HUMAN (1-593): 0: 726: 100.00		TRIM6_HUMAN (176-490): 9.28e-55: 200: 16.30