HitPredict

Interactor 1: NIP80 (P33420)
Protein NIP100 (Protein NIP80)
Gene: NIP100

Interactor 2: NDC80 (P40460)
Kinetochore protein NDC80 (80 kDa spindle component protein) (Nuclear division cycle protein 80) (Two-hybrid interaction with DMC1 protein 3)
Gene: NDC80

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.595

Property	Details
Experiments	10688190, 17634282
Identification Methods	two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 868 Sc			1 691
+	Hs
		154992 CE350_HUMAN (4-392): 5.53e-41: 166: 21.16		NDC80_HUMAN (81-681): 2.42e-36: 147: 19.61
+	Hs
		154959 DCTN1_HUMAN (68-387): 1.4e-16: 86.8: 10.90		NDC80_HUMAN (81-681): 2.42e-36: 147: 19.61
+	Hs
		1051319 CE350_HUMAN (4-392): 5.53e-41: 166: 21.16		DCTN1_HUMAN (414-689): 2.74e-09: 62.6: 12.41
+	Rn
		1186812 MRCKB_RAT (62-488): 4.21e-22: 104: 13.90		MRCKB_RAT (172-620): 6.55e-24: 110: 11.47
+	Rn
		222476 MRCKB_RAT (62-488): 4.21e-22: 104: 13.90		MRCKA_RAT (171-600): 2.74e-21: 101: 12.33
+	Hs
		1268126 MY18A_HUMAN (63-795): 7.75e-18: 91.4: 12.48		MRCKB_HUMAN (335-691): 1.98e-23: 108: 12.77
+	Hs
		1137917 MRCKB_HUMAN (215-750): 1.61e-16: 86.8: 13.84		MRCKA_HUMAN (171-600): 2.62e-20: 98.6: 11.88
+	Hs
		725033 KI13B_HUMAN (4-135): 3.14e-25: 115: 25.36		MYH9_HUMAN (333-691): 2.87e-11: 69.5: 13.44
+	Hs
		1078925 CLIP2_HUMAN (5-506): 3.13e-26: 118: 18.11		ITSN1_HUMAN (440-691): 1.27e-09: 64: 8.68
+	Hs
		1137871 MRCKA_HUMAN (243-734): 1.6e-12: 73.7: 13.49		MRCKA_HUMAN (171-600): 2.62e-20: 98.6: 11.88
+	Hs
		1268060 MY18A_HUMAN (63-795): 7.75e-18: 91.4: 12.48		MY18A_HUMAN (264-674): 1.96e-12: 73: 16.20
+	Hs
		724943 MY18A_HUMAN (63-795): 7.75e-18: 91.4: 12.48		MYH9_HUMAN (333-691): 2.87e-11: 69.5: 13.44
+	Hs
		502921 CLIP4_HUMAN (10-90): 3.3e-18: 91.8: 30.12		MYH3_HUMAN (226-613): 1.24e-09: 64.1: 11.34
+	Hs
		149126 MY18A_HUMAN (63-795): 7.75e-18: 91.4: 12.48		CTRO_HUMAN (301-647): 2.93e-09: 62.6: 15.16
+	Rn
		655923 DCTN1_RAT (68-387): 5.17e-16: 85.3: 10.25		DCTN1_RAT (320-641): 2.29e-10: 66.1: 14.33
+	Hs
		1051273 DCTN1_HUMAN (68-387): 1.4e-16: 86.8: 10.90		DCTN1_HUMAN (414-689): 2.74e-09: 62.6: 12.41
+	Hs
		148801 DCTN1_HUMAN (68-387): 1.4e-16: 86.8: 10.90		CTRO_HUMAN (301-647): 2.93e-09: 62.6: 15.16
+	Dm
		1001870 Q0KI67_DROME (200-767): 1.99e-12: 73.7: 14.58		Q0KI67_DROME (237-686): 1.8e-10: 66.9: 14.82