Protein: LEG8
Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1)

Gene: LEG8, LGALS8
Organism: Homo sapiens
Interactions: 192
UniProt ID: O00214

Gene Ontology (top 5):
GO:0005178 - integrin binding
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

121158

NECT1
Nectin-1

3

6

High-throughput

0.861

High

121171

CD276
CD276 antigen

3

4

High-throughput

0.861

High

119005

LEG9
Galectin-9

2

16

Small-scale

0.789

High

121126

MUC18
Cell surface glycoprotein MUC18

2

8

High-throughput

0.789

High

121220

FPRP
Prostaglandin F2 receptor negative regulator

3

7

High-throughput

0.770

High

121148

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

15

7

Small-scale

0.764

High

121184

TAXB1
Tax1-binding protein 1

9

7

Small-scale

0.756

High

121077

ITB1
Integrin beta-1

8

12

Small-scale

0.750

High

121110

ITA3
Integrin alpha-3

6

20

Small-scale

0.736

High

121084

ITA5
Integrin alpha-5

6

20

Small-scale

0.730

High

121095

ITA4
Integrin alpha-4

5

20

Small-scale

0.721

High

121215

NECT3
Nectin-3

2

12

High-throughput

0.705

High

121052

SDCB1
Syntenin-1

4

8

Small-scale

0.694

High

121135

ITA1
Integrin alpha-1

4

20

Small-scale

0.694

High

121228

TRIM1
Probable E3 ubiquitin-protein ligase MID2

3

19

High-throughput

0.675

High

121121

TRI23
E3 ubiquitin-protein ligase TRIM23

3

4

Small-scale

0.669

High

121053

PODXL
Podocalyxin

3

5

High-throughput

0.667

High

121056

MRP4
ATP-binding cassette sub-family C member 4

3

13

High-throughput

0.667

High

121058

ADCY6
Adenylate cyclase type 6

3

7

High-throughput

0.667

High

121059

RNF13
E3 ubiquitin-protein ligase RNF13

3

3

High-throughput

0.667

High

121060

SUSD5
Sushi domain-containing protein 5

3

2

High-throughput

0.667

High

121062

ADCY9
Adenylate cyclase type 9

3

7

High-throughput

0.667

High

121070

FINC
Fibronectin

3

18

High-throughput

0.667

High

121076

B3A2
Anion exchange protein 2

3

10

High-throughput

0.667

High

121086

CD63
CD63 antigen

3

8

High-throughput

0.667

High

121088

CO4A
Complement C4-A

3

7

High-throughput

0.667

High

121091

PPAL
Lysosomal acid phosphatase

3

3

High-throughput

0.667

High

121102

ITA2
Integrin alpha-2

3

20

High-throughput

0.667

High

121103

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

3

20

High-throughput

0.667

High

121104

LFA3
Lymphocyte function-associated antigen 3

3

3

High-throughput

0.667

High

121107

ITA6
Integrin alpha-6

3

20

High-throughput

0.667

High

121109

AT2B4
Plasma membrane calcium-transporting ATPase 4

3

11

High-throughput

0.667

High

121120

VGFR3
Vascular endothelial growth factor receptor 3

3

6

High-throughput

0.667

High

121125

EAA3
Excitatory amino acid transporter 3

3

6

High-throughput

0.667

High

121127

S26A2
Sulfate transporter

3

5

High-throughput

0.667

High

121129

CLCN3
H(+)/Cl(-) exchange transporter 3

3

8

High-throughput

0.667

High

121130

CLCN5
H(+)/Cl(-) exchange transporter 5

3

8

High-throughput

0.667

High

121131

CLCN7
H(+)/Cl(-) exchange transporter 7

3

8

High-throughput

0.667

High

121133

S12A2
Solute carrier family 12 member 2

3

20

High-throughput

0.667

High

121142

AT2B2
Plasma membrane calcium-transporting ATPase 2

3

9

High-throughput

0.667

High

121150

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

3

20

High-throughput

0.667

High

121154

DAG1
Dystroglycan 1

3

5

High-throughput

0.667

High

121159

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

20

High-throughput

0.667

High

121165

ANO6
Anoctamin-6

3

4

High-throughput

0.667

High

121167

COL12
Collectin-12

3

8

High-throughput

0.667

High

121170

RRAGB
Ras-related GTP-binding protein B

3

9

High-throughput

0.667

High

121175

LRC8E
Volume-regulated anion channel subunit LRRC8E

3

5

High-throughput

0.667

High

121182

ATG9A
Autophagy-related protein 9A

3

5

High-throughput

0.667

High

121185

OSTM1
Osteopetrosis-associated transmembrane protein 1

3

2

High-throughput

0.667

High

121187

LRC8A
Volume-regulated anion channel subunit LRRC8A

3

5

High-throughput

0.667

High

121189

K319L
Dyslexia-associated protein KIAA0319-like protein

3

3

High-throughput

0.667

High

121193

SPP2A
Signal peptide peptidase-like 2A

3

1

High-throughput

0.667

High

121194

TRPM4
Transient receptor potential cation channel subfamily M member 4

3

2

High-throughput

0.667

High

121195

LRC8C
Volume-regulated anion channel subunit LRRC8C

3

5

High-throughput

0.667

High

121199

SORL
Sortilin-related receptor

3

5

High-throughput

0.667

High

121209

S12A9
Solute carrier family 12 member 9

3

20

High-throughput

0.667

High

121212

AT133
Polyamine-transporting ATPase 13A3

3

13

High-throughput

0.667

High

121213

RRAGC
Ras-related GTP-binding protein C

3

9

High-throughput

0.667

High

121217

S17A5
Sialin

3

2

High-throughput

0.667

High

121221

MRC2
C-type mannose receptor 2

3

20

High-throughput

0.667

High

121226

S12A6
Solute carrier family 12 member 6

3

20

High-throughput

0.667

High

121227

LCAP
Leucyl-cystinyl aminopeptidase

3

5

High-throughput

0.667

High

121232

S12A4
Solute carrier family 12 member 4

3

20

High-throughput

0.667

High

121237

ZNT1
Proton-coupled zinc antiporter SLC30A1

3

3

High-throughput

0.667

High

121238

S4A7
Sodium bicarbonate cotransporter 3

3

10

High-throughput

0.667

High

121239

ENPP4
Bis(5'-adenosyl)-triphosphatase ENPP4

3

4

High-throughput

0.667

High

121051

LEG8
Galectin-8

1

14

Small-scale

0.647

High

121204

CA159
Uncharacterized protein C1orf159

3

0

High-throughput

0.638

High

121205

TM237
Transmembrane protein 237

3

0

High-throughput

0.638

High

121168

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

1

Small-scale

0.629

High

121124

ECE1
Endothelin-converting enzyme 1

2

4

High-throughput

0.628

High

121097

ACPH
Acylamino-acid-releasing enzyme

2

2

High-throughput

0.628

High

121054

NPC1
NPC intracellular cholesterol transporter 1

2

2

High-throughput

0.611

High

121201

VPP1
V-type proton ATPase 116 kDa subunit a 1

2

6

High-throughput

0.611

High

121065

CSCL1
CSC1-like protein 1

3

6

High-throughput

0.609

High

121108

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

3

20

High-throughput

0.609

High

121134

MFAP3
Microfibril-associated glycoprotein 3

3

3

High-throughput

0.609

High

121145

CD47
Leukocyte surface antigen CD47

3

2

High-throughput

0.609

High

121146

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

3

20

High-throughput

0.609

High

121151

CD166
CD166 antigen

3

9

High-throughput

0.609

High

121163

LAMA4
Laminin subunit alpha-4

3

16

High-throughput

0.609

High

121164

AT2B3
Plasma membrane calcium-transporting ATPase 3

3

11

High-throughput

0.609

High

121169

CSCL2
CSC1-like protein 2

3

6

High-throughput

0.609

High

121177

EMB
Embigin

3

8

High-throughput

0.609

High

121178

CSPG4
Chondroitin sulfate proteoglycan 4

3

13

High-throughput

0.609

High

121179

SE6L2
Seizure 6-like protein 2

3

6

High-throughput

0.609

High

121183

SDK1
Protein sidekick-1

3

15

High-throughput

0.609

High

121191

S38A9
Neutral amino acid transporter 9

3

3

High-throughput

0.609

High

121198

SL9A6
Sodium/hydrogen exchanger 6

3

3

High-throughput

0.609

High

121214

K1549
UPF0606 protein KIAA1549

3

11

High-throughput

0.609

High

121229

HEG1
Protein HEG homolog 1

3

13

High-throughput

0.609

High

121233

VPP2
V-type proton ATPase 116 kDa subunit a 2

3

6

High-throughput

0.609

High

121236

S12A7
Solute carrier family 12 member 7

3

20

High-throughput

0.609

High

121206

NACC1
Nucleus accumbens-associated protein 1

2

2

High-throughput

0.606

High

121197

GLMP
Glycosylated lysosomal membrane protein

2

0

High-throughput

0.585

High

121202

WBP2
WW domain-binding protein 2

2

0

High-throughput

0.580

High

121075

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

6

High-throughput

0.576

High

121218

LRC4B
Leucine-rich repeat-containing protein 4B

2

6

High-throughput

0.574

High

121072

ESR1
Estrogen receptor

2

7

High-throughput

0.571

High

121074

ANXA1
Annexin A1

2

10

Small-scale

0.563

High

121207

BARD1
BRCA1-associated RING domain protein 1

1

2

High-throughput

0.552

High

121063

DJC13
DnaJ homolog subfamily C member 13

1

3

High-throughput

0.536

High

121100

CD44
CD44 antigen

1

6

High-throughput

0.536

High

121101

LEUK
Leukosialin

1

2

High-throughput

0.536

High

121117

MRP1
Multidrug resistance-associated protein 1

1

13

High-throughput

0.536

High

121173

SIGIR
Single Ig IL-1-related receptor

1

1

High-throughput

0.536

High

121203

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

1

4

High-throughput

0.536

High

121224

TBK1
Serine/threonine-protein kinase TBK1

1

4

High-throughput

0.536

High

121225

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

2

High-throughput

0.536

High

121230

ICAM5
Intercellular adhesion molecule 5

1

7

High-throughput

0.536

High

121112

CALR
Calreticulin

1

4

High-throughput

0.515

High

121122

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.515

High

121196

NEK7
Serine/threonine-protein kinase Nek7

1

2

High-throughput

0.515

High

121116

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.513

High

121149

CUL1
Cullin-1

1

0

High-throughput

0.513

High

121057

MEFV
Pyrin

1

12

Small-scale

0.501

High

121089

TRI49
Tripartite motif-containing protein 49

1

13

Small-scale

0.501

High

121188

TRI22
E3 ubiquitin-protein ligase TRIM22

1

13

Small-scale

0.501

High

121210

TRIM6
Tripartite motif-containing protein 6

1

13

Small-scale

0.501

High

121211

TRIM5
Tripartite motif-containing protein 5

1

13

Small-scale

0.501

High

121234

TRI17
E3 ubiquitin-protein ligase TRIM17

1

12

Small-scale

0.501

High

121192

VANG1
Vang-like protein 1

1

1

High-throughput

0.489

High

121219

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

1

High-throughput

0.489

High

121235

NPTN
Neuroplastin

1

10

High-throughput

0.489

High

121156

NR1D2
Nuclear receptor subfamily 1 group D member 2

1

7

High-throughput

0.481

High

121067

EGFR
Epidermal growth factor receptor

1

6

High-throughput

0.479

High

121068

A2MG
Alpha-2-macroglobulin

1

7

Small-scale

0.479

High

121069

APOA1
Apolipoprotein A-I

1

3

Small-scale

0.479

High

121071

HEMO
Hemopexin

1

5

Small-scale

0.479

High

121073

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

121078

ITAV
Integrin alpha-V

1

20

Small-scale

0.479

High

121079

PDIA1
Protein disulfide-isomerase

1

6

Small-scale

0.479

High

121080

ANXA2
Annexin A2

1

8

Small-scale

0.479

High

121081

HS90A
Heat shock protein HSP 90-alpha

1

5

Small-scale

0.479

High

121082

RHOC
Rho-related GTP-binding protein RhoC

1

5

Small-scale

0.479

High

121083

MMP3
Stromelysin-1

1

6

Small-scale

0.479

High

121085

ANXA5
Annexin A5

1

10

Small-scale

0.479

High

121087

HMGB1
High mobility group protein B1

1

5

Small-scale

0.479

High

121090

THIO
Thioredoxin

1

5

Small-scale

0.479

High

121092

LAMP1
Lysosome-associated membrane glycoprotein 1

1

10

Small-scale

0.479

High

121093

FGFR1
Fibroblast growth factor receptor 1

1

7

High-throughput

0.479

High

121094

LAMP2
Lysosome-associated membrane glycoprotein 2

1

10

Small-scale

0.479

High

121096

PDIA4
Protein disulfide-isomerase A4

1

6

Small-scale

0.479

High

121098

ENPL
Endoplasmin

1

5

Small-scale

0.479

High

121099

MMP9
Matrix metalloproteinase-9

1

16

Small-scale

0.479

High

121105

BTF3
Transcription factor BTF3

1

1

High-throughput

0.479

High

121106

ITAL
Integrin alpha-L

1

20

Small-scale

0.479

High

121111

HMGB2
High mobility group protein B2

1

5

Small-scale

0.479

High

121113

CALX
Calnexin

1

4

Small-scale

0.479

High

121114

GDIA
Rab GDP dissociation inhibitor alpha

1

1

Small-scale

0.479

High

121115

PRDX2
Peroxiredoxin-2

1

6

Small-scale

0.479

High

121118

CD68
Macrosialin

1

10

Small-scale

0.479

High

121128

RAB7A
Ras-related protein Rab-7a

1

2

Small-scale

0.479

High

121136

CDC42
Cell division control protein 42 homolog

1

5

Small-scale

0.479

High

121137

RAB14
Ras-related protein Rab-14

1

4

Small-scale

0.479

High

121139

1433G
14-3-3 protein gamma

1

8

Small-scale

0.479

High

121140

1433E
14-3-3 protein epsilon

1

1

Small-scale

0.479

High

121143

PRDX1
Peroxiredoxin-1

1

6

Small-scale

0.479

High

121144

LG3BP
Galectin-3-binding protein

1

6

Small-scale

0.479

High

121152

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

7

High-throughput

0.479

High

121153

SCRB2
Lysosome membrane protein 2

1

1

High-throughput

0.479

High

121157

PDIA6
Protein disulfide-isomerase A6

1

6

Small-scale

0.479

High

121166

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

1

High-throughput

0.479

High

121216

ANLN
Anillin

1

1

High-throughput

0.479

High

121222

HDAC6
Histone deacetylase 6

1

2

High-throughput

0.479

High

121176

Q6NSM0
NR1D2 protein

1

10

High-throughput

0.470

High

121061

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

121066

SODC
Superoxide dismutase [Cu-Zn]

1

0

Small-scale

0.458

High

121132

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

Small-scale

0.458

High

121138

LYSC
Lysozyme C

1

0

Small-scale

0.458

High

121141

NDP
Norrin

1

0

Small-scale

0.458

High

121186

PDPN
Podoplanin

1

0

Small-scale

0.458

High

121223

CATZ
Cathepsin Z

1

0

Small-scale

0.458

High

121231

EPCR
Endothelial protein C receptor

1

0

High-throughput

0.458

High

121119

BMI1
Polycomb complex protein BMI-1

1

13

High-throughput

0.445

High

121123

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

High-throughput

0.445

High

121174

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.445

High

121190

S15A4
Solute carrier family 15 member 4

1

3

Small-scale

0.445

High

121147

PDIA2
Protein disulfide-isomerase A2

1

4

Small-scale

0.437

High

121155

ITIH4
Inter-alpha-trypsin inhibitor heavy chain H4

1

2

Small-scale

0.437

High

121161

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.437

High

121172

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

12

High-throughput

0.437

High

121200

ESR2
Estrogen receptor beta

1

5

High-throughput

0.437

High

121162

NF2L2
Nuclear factor erythroid 2-related factor 2

1

0

High-throughput

0.426

High

49719

S22AN
Solute carrier family 22 member 23

3

0

High-throughput

0.347

High

121055

COPT1
High affinity copper uptake protein 1

3

0

High-throughput

0.347

High

121180

SV2A
Synaptic vesicle glycoprotein 2A

3

0

High-throughput

0.347

High

121181

S36A1
Proton-coupled amino acid transporter 1

3

0

High-throughput

0.347

High

121208

S35A5
UDP-sugar transporter protein SLC35A5

3

0

High-throughput

0.347

High

121160

TGIF1
Homeobox protein TGIF1

1

0

Small-scale

0.276

Low

121064

WFS1
Wolframin

1

0

High-throughput

0.268

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024