Protein: VMAT1
Chromaffin granule amine transporter (Solute carrier family 18 member 1) (Vesicular amine transporter 1) (VAT1)

Gene: VMAT1, SLC18A1
Organism: Homo sapiens
Interactions: 177
UniProt ID: P54219

Gene Ontology (top 5):
GO:0005335 - serotonin:sodium:chloride symporter activity
GO:0005789 - endoplasmic reticulum membrane
GO:0008504 - monoamine transmembrane transporter activity
GO:0015311 - monoamine:proton antiporter activity
GO:0015842 - aminergic neurotransmitter loading into synaptic vesicle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

926849

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

3

1

High-throughput

0.667

High

215523

EMC8
ER membrane protein complex subunit 8

3

0

High-throughput

0.638

High

926779

EMC4
ER membrane protein complex subunit 4

3

0

High-throughput

0.634

High

926809

SFXN5
Sideroflexin-5

4

3

High-throughput

0.630

High

248576

FADS1
Acyl-CoA

2

8

High-throughput

0.628

High

295810

FACE1
CAAX prenyl protease 1 homolog

2

1

High-throughput

0.628

High

783035

CXG1
Gap junction gamma-1 protein

2

1

High-throughput

0.628

High

926805

AN13C
Ankyrin repeat domain-containing protein 13C

2

7

High-throughput

0.628

High

926826

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

2

5

High-throughput

0.628

High

926832

S29A1
Equilibrative nucleoside transporter 1

2

4

High-throughput

0.628

High

926850

PXMP2
Peroxisomal membrane protein 2

3

4

High-throughput

0.609

High

336157

CNIH1
Protein cornichon homolog 1

2

2

High-throughput

0.606

High

926763

PLP2
Proteolipid protein 2

2

1

High-throughput

0.606

High

926774

S35G1
Solute carrier family 35 member G1

2

2

High-throughput

0.606

High

926790

ATRAP
Type-1 angiotensin II receptor-associated protein

2

1

High-throughput

0.606

High

926802

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

6

High-throughput

0.606

High

926810

GP151
G-protein coupled receptor 151

2

2

High-throughput

0.606

High

926817

S35B4
Nucleotide sugar transporter SLC35B4

2

5

High-throughput

0.606

High

926862

ORML1
ORM1-like protein 1

2

8

High-throughput

0.606

High

926874

PEX16
Peroxisomal membrane protein PEX16

2

1

High-throughput

0.606

High

926876

TM14A
Transmembrane protein 14A

2

2

High-throughput

0.606

High

155450

C2C2L
Phospholipid transfer protein C2CD2L

2

0

High-throughput

0.580

High

156551

C56D2
Transmembrane reductase CYB561D2

2

0

High-throughput

0.580

High

926768

FXYD3
FXYD domain-containing ion transport regulator 3

2

0

High-throughput

0.580

High

926804

TM86A
Lysoplasmalogenase TMEM86A

2

0

High-throughput

0.580

High

926814

GIMA1
GTPase IMAP family member 1

2

0

High-throughput

0.580

High

926818

TM203
Transmembrane protein 203

2

0

High-throughput

0.580

High

926834

APOL2
Apolipoprotein L2

2

0

High-throughput

0.580

High

665081

COT2
COUP transcription factor 2

2

2

High-throughput

0.574

High

755538

TTK
Dual specificity protein kinase TTK

2

3

High-throughput

0.574

High

908905

NEK4
Serine/threonine-protein kinase Nek4

2

3

High-throughput

0.574

High

926759

ARF5
ADP-ribosylation factor 5

2

3

High-throughput

0.574

High

926783

ECM29
Proteasome adapter and scaffold protein ECM29

2

3

High-throughput

0.574

High

926808

SPPL3
Signal peptide peptidase-like 3

2

5

High-throughput

0.574

High

926811

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

2

3

High-throughput

0.574

High

926820

OTUL
Ubiquitin thioesterase otulin

2

2

High-throughput

0.574

High

926842

S12A9
Solute carrier family 12 member 9

2

11

High-throughput

0.574

High

926864

FA8A1
Protein FAM8A1

2

2

High-throughput

0.574

High

926870

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

2

3

High-throughput

0.574

High

926871

RHBD3
Rhomboid domain-containing protein 3

2

4

High-throughput

0.574

High

926769

EMC2
ER membrane protein complex subunit 2

2

2

High-throughput

0.571

High

922297

LIMK2
LIM domain kinase 2

2

4

High-throughput

0.558

High

926771

PDK1
[Pyruvate dehydrogenase

2

2

High-throughput

0.558

High

49638

T120B
Transmembrane protein 120B

2

2

High-throughput

0.553

High

390501

TFR1
Transferrin receptor protein 1

2

5

High-throughput

0.553

High

561031

CCL4
C-C motif chemokine 4

2

1

High-throughput

0.553

High

706016

CXB2
Gap junction beta-2 protein

2

1

High-throughput

0.553

High

719058

MIP
Lens fiber major intrinsic protein

2

2

High-throughput

0.553

High

746186

STX2
Syntaxin-2

2

3

High-throughput

0.553

High

926789

BRID5
BRICHOS domain-containing protein 5

2

1

High-throughput

0.553

High

926792

OLFM4
Olfactomedin-4

2

1

High-throughput

0.553

High

926800

ANR46
Ankyrin repeat domain-containing protein 46

2

3

High-throughput

0.553

High

926806

CC4L
C-C motif chemokine 4-like

2

1

High-throughput

0.553

High

926816

FAM3C
Protein FAM3C

2

1

High-throughput

0.553

High

926823

YIPF6
Protein YIPF6

2

5

High-throughput

0.553

High

926836

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

6

High-throughput

0.553

High

926838

YIPF4
Protein YIPF4

2

5

High-throughput

0.553

High

926848

S39A2
Zinc transporter ZIP2

2

1

High-throughput

0.553

High

926855

TM14B
Transmembrane protein 14B

2

2

High-throughput

0.553

High

926856

S38A7
Sodium-coupled neutral amino acid transporter 7

2

3

High-throughput

0.553

High

926869

STX8
Syntaxin-8

2

2

High-throughput

0.553

High

122606

UBXN8
UBX domain-containing protein 8

1

1

High-throughput

0.536

High

520793

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

2

High-throughput

0.536

High

926753

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

1

7

High-throughput

0.536

High

926767

ERG1
Squalene monooxygenase

1

4

High-throughput

0.536

High

926772

NOMO1
BOS complex subunit NOMO1

1

2

High-throughput

0.536

High

926793

HACD2
Very-long-chain

1

6

High-throughput

0.536

High

926840

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

3

High-throughput

0.536

High

926852

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

9

High-throughput

0.536

High

926859

EMC3
ER membrane protein complex subunit 3

1

1

High-throughput

0.536

High

926812

BT2A2
Butyrophilin subfamily 2 member A2

1

0

High-throughput

0.519

High

926825

SRAC1
Protein SERAC1

1

0

High-throughput

0.513

High

333566

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

1

High-throughput

0.489

High

926758

TBA4A
Tubulin alpha-4A chain

1

1

High-throughput

0.489

High

926761

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

1

4

High-throughput

0.489

High

926786

TYW1B
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B

1

2

High-throughput

0.489

High

926787

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

3

High-throughput

0.489

High

926798

ADCK1
AarF domain-containing protein kinase 1

1

3

High-throughput

0.489

High

926815

CTR3
Cationic amino acid transporter 3

1

9

High-throughput

0.489

High

926819

PAQR1
Adiponectin receptor protein 1

1

2

High-throughput

0.489

High

926822

RSPRY
RING finger and SPRY domain-containing protein 1

1

2

High-throughput

0.489

High

144420

SCD
Stearoyl-CoA desaturase

1

2

High-throughput

0.481

High

226316

SNG1
Synaptogyrin-1

1

3

High-throughput

0.481

High

332935

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

2

High-throughput

0.481

High

926781

TSPO2
Translocator protein 2

1

1

High-throughput

0.481

High

926797

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

5

High-throughput

0.481

High

926831

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

1

6

High-throughput

0.481

High

926841

TM147
BOS complex subunit TMEM147

1

2

High-throughput

0.481

High

926860

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.481

High

926861

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

1

High-throughput

0.481

High

926865

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

1

High-throughput

0.481

High

403148

APOB
Apolipoprotein B-100

1

2

High-throughput

0.479

High

926754

RAB38
Ras-related protein Rab-38

1

6

High-throughput

0.470

High

926775

Q59EV6
Carboxypeptidase

1

2

High-throughput

0.470

High

926824

SC22A
Vesicle-trafficking protein SEC22a

1

0

High-throughput

0.460

High

926830

MGLL
Monoglyceride lipase

1

0

High-throughput

0.460

High

926857

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.460

High

926873

INSI2
Insulin-induced gene 2 protein

1

0

High-throughput

0.460

High

926875

SELK
Selenoprotein K

1

0

High-throughput

0.460

High

926877

SERP1
Stress-associated endoplasmic reticulum protein 1

1

0

High-throughput

0.460

High

926782

EMC10
ER membrane protein complex subunit 10

1

0

High-throughput

0.458

High

170715

CLGN
Calmegin

1

7

High-throughput

0.445

High

609632

LEG3
Galectin-3

1

10

High-throughput

0.445

High

749603

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

3

High-throughput

0.445

High

926829

SORT
Sortilin

1

2

High-throughput

0.445

High

189478

STX7
Syntaxin-7

1

2

High-throughput

0.439

High

295677

UPK1B
Uroplakin-1b

1

3

High-throughput

0.439

High

528668

PPGB
Lysosomal protective protein

1

2

High-throughput

0.439

High

926755

CD81
CD81 antigen

1

2

High-throughput

0.439

High

926863

TM14C
Transmembrane protein 14C

1

2

High-throughput

0.439

High

926866

AGRE2
Adhesion G protein-coupled receptor E2

1

5

High-throughput

0.439

High

926867

PRAF1
Prenylated Rab acceptor protein 1

1

2

High-throughput

0.439

High

926872

YIPF1
Protein YIPF1

1

3

High-throughput

0.439

High

328235

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

1

High-throughput

0.437

High

612948

EGR1
Early growth response protein 1

1

1

High-throughput

0.437

High

760417

SDC2
Syndecan-2

1

1

High-throughput

0.437

High

926773

OCLN
Occludin

1

1

High-throughput

0.437

High

926778

MTX3
Metaxin-3

1

5

High-throughput

0.437

High

926833

MICU1
Calcium uptake protein 1, mitochondrial

1

2

High-throughput

0.437

High

81637

B5MC51
Protein phosphatase 1 regulatory subunit 14

1

4

High-throughput

0.407

High

85095

B7Z207
Protein-serine/threonine kinase

1

2

High-throughput

0.407

High

231464

ORC4
Origin recognition complex subunit 4

1

5

High-throughput

0.407

High

317151

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

1

High-throughput

0.407

High

409567

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

3

High-throughput

0.407

High

674116

BRD2
Bromodomain-containing protein 2

1

1

High-throughput

0.407

High

726646

SDC4
Syndecan-4

1

1

High-throughput

0.407

High

926757

RAB14
Ras-related protein Rab-14

1

3

High-throughput

0.407

High

926766

IL27B
Interleukin-27 subunit beta

1

3

High-throughput

0.407

High

926770

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

5

High-throughput

0.407

High

926801

WDFY1
WD repeat and FYVE domain-containing protein 1

1

1

High-throughput

0.407

High

926807

NPL4
Nuclear protein localization protein 4 homolog

1

2

High-throughput

0.407

High

926827

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

1

High-throughput

0.407

High

926835

MGME1
Mitochondrial genome maintenance exonuclease 1

1

1

High-throughput

0.407

High

926845

PCX3
Pecanex-like protein 3

1

2

High-throughput

0.407

High

219614

B2L11
Bcl-2-like protein 11

2

0

High-throughput

0.328

High

926796

DPH6
Diphthine--ammonia ligase

2

0

High-throughput

0.328

High

926821

EVI5L
EVI5-like protein

2

0

High-throughput

0.328

High

926837

PXL2A
Peroxiredoxin-like 2A

2

0

High-throughput

0.328

High

60562

TM218
Transmembrane protein 218

2

0

High-throughput

0.316

High

74158

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.316

High

216316

MGA
Maltase-glucoamylase

2

0

High-throughput

0.316

High

220365

LAT
Linker for activation of T-cells family member 1

2

0

High-throughput

0.316

High

328649

VAMP5
Vesicle-associated membrane protein 5

2

0

High-throughput

0.316

High

549432

CD20
B-lymphocyte antigen CD20

2

0

High-throughput

0.316

High

712093

CO4A5

2

0

High-throughput

0.316

High

926752

LIPR1
Inactive pancreatic lipase-related protein 1

2

0

High-throughput

0.316

High

926756

MYPR
Myelin proteolipid protein

2

0

High-throughput

0.316

High

926760

PMP22
Peripheral myelin protein 22

2

0

High-throughput

0.316

High

926764

MALL
MAL-like protein

2

0

High-throughput

0.316

High

926777

TM128
Transmembrane protein 128

2

0

High-throughput

0.316

High

926780

M4A13
Membrane-spanning 4-domains subfamily A member 13

2

0

High-throughput

0.316

High

926785

TMM42
Transmembrane protein 42

2

0

High-throughput

0.316

High

926788

TMM65
Transmembrane protein 65

2

0

High-throughput

0.316

High

926794

MFSD6
Major facilitator superfamily domain-containing protein 6

2

0

High-throughput

0.316

High

926803

NRM
Nurim

2

0

High-throughput

0.316

High

926813

TM239
Transmembrane protein 239

2

0

High-throughput

0.316

High

926828

NEUR1
Sialidase-1

2

0

High-throughput

0.316

High

926844

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

926851

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

2

0

High-throughput

0.316

High

926854

RPRM
Protein reprimo

2

0

High-throughput

0.316

High

926784

F91A1
Protein FAM91A1

1

0

High-throughput

0.279

Low

926846

NJMU
Protein Njmu-R1

1

0

High-throughput

0.279

Low

926847

EKI1
Ethanolamine kinase 1

1

0

High-throughput

0.279

Low

926858

RTEL1
Regulator of telomere elongation helicase 1

1

0

High-throughput

0.279

Low

139197

UPK2
Uroplakin-2

1

0

High-throughput

0.251

Low

718683

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.251

Low

926776

SGMR2
Sigma intracellular receptor 2

1

0

High-throughput

0.251

Low

926839

HTAI2
Protein HTATIP2

1

0

High-throughput

0.251

Low

926843

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.251

Low

926853

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

0

High-throughput

0.251

Low

873364

AL3B2
Aldehyde dehydrogenase family 3 member B2

1

0

High-throughput

0.249

Low

926791

TM205
Transmembrane protein 205

1

0

High-throughput

0.249

Low

926762

ACY1
Aminoacylase-1

1

0

High-throughput

0.232

Low

926765

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.232

Low

926795

TM1L2
TOM1-like protein 2

1

0

High-throughput

0.232

Low

926799

VPS36
Vacuolar protein-sorting-associated protein 36

1

0

High-throughput

0.232

Low

926868

MYO6
Unconventional myosin-VI

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025