Interactor 1: MMP13 (P33435)
Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)
Gene: MMP13
Interactor 2: TIMP3 (P39876)
Metalloproteinase inhibitor 3 (Tissue inhibitor of metalloproteinases 3) (TIMP-3)
Gene: TIMP3
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18295466 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Hemopexin~TIMP, Peptidase_M10~TIMP |
| Common GO terms | GO:0005615 - extracellular space GO:0008270 - zinc ion binding GO:0009725 - response to hormone GO:0031012 - extracellular matrix |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
