HitPredict

Interactor 1: MRP1 (P33527)
Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter)
Gene: ABCC1

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1531 Hs			1 196
+	Hs
		706702 MRP1_HUMAN (1-1531): 0: 1288: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		706695 MRP1_HUMAN (1-1531): 0: 1288: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		545225 MRP1_HUMAN (1-1531): 0: 1288: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436176 MRP1_HUMAN (1-1531): 0: 1288: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		706705 MRP1_HUMAN (1-1531): 0: 1288: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		706692 MRP1_HUMAN (1-1531): 0: 1288: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		706693 MRP1_HUMAN (1-1531): 0: 1288: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564426 MRP1_HUMAN (1-1531): 0: 1288: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120319 MRP1_HUMAN (1-1531): 0: 1288: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Sc
		419697 YCFI_YEAST (27-1531): 0: 980: 38.73		RHO1_YEAST (3-186): 1.7e-88: 260: 67.39
+	Hs
		179406 MRP5_HUMAN (201-1524): 0: 840: 32.39		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		179403 MRP5_HUMAN (201-1524): 0: 840: 32.39		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		179405 MRP5_HUMAN (201-1524): 0: 840: 32.39		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		179393 MRP5_HUMAN (201-1524): 0: 840: 32.39		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		179391 MRP5_HUMAN (201-1524): 0: 840: 32.39		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		179408 MRP5_HUMAN (201-1524): 0: 840: 32.39		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		179400 MRP5_HUMAN (201-1524): 0: 840: 32.39		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		179401 MRP5_HUMAN (201-1524): 0: 840: 32.39		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		179395 MRP5_HUMAN (201-1524): 0: 840: 32.39		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120217 MRP5_HUMAN (201-1524): 0: 840: 32.39		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98