Interactor 1: NPL4 (P33755)
Nuclear protein localization protein 4 (HMG-CoA reductase degradation protein 4)
Gene: NPL4

Interactor 2: UFD1 (P53044)
Ubiquitin fusion degradation protein 1 (UB fusion protein 1) (Polymerase-interacting protein 3)
Gene: UFD1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.766

The method score is based on:

Property Details
Experiments 11283351, 23624404, 11733065, 10688190, 11805826, 11598205, 16429126, 16179952, 31836717, 37311459, 37968396, 21211725, 22940862, 17289586, 16554755, 32804080, 36736315, 36574706, 21070972
Identification Methods two hybrid pooling approach, pull down, two hybrid, coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000837 - Doa10p ubiquitin ligase complex
GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0005634 - nucleus
GO:0006274 - DNA replication termination
GO:0030894 - replisome
and 13 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 580
Sc

1 361
+ Rn
+ Hs
+ Xl
+ Sp
+ Dm
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024