HitPredict

Interactor 1: H2B1B (P33778)
Histone H2B type 1-B (H2B-clustered histone 3) (Histone H2B.1) (Histone H2B.f) (H2B/f)
Gene: H2BC3

Interactor 2: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	11003660
Identification Methods	affinity chromatography technology, far western blotting
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 1493
+	Hs
		241591 H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83		CHD5_HUMAN (300-1446): 0: 783: 19.15
+	Hs
		1087449 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		CHD7_HUMAN (3-1479): 0: 774: 17.81
+	Hs
		707647 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		CHD9_HUMAN (3-1492): 0: 774: 18.73
+	Hs
		707773 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		CHD7_HUMAN (3-1479): 0: 774: 17.81
+	Hs
		1059648 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		CHD4_HUMAN (303-1439): 0: 766: 18.35
+	Hs
		1059777 H2B1H_HUMAN (1-126): 6.88e-55: 169: 96.83		CHD4_HUMAN (303-1439): 0: 766: 18.35
+	Hs
		241527 H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83		CHD4_HUMAN (303-1439): 0: 766: 18.35
+	Hs
		707635 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		CHD4_HUMAN (303-1439): 0: 766: 18.35
+	Hs
		1018625 H2B1H_HUMAN (1-126): 6.88e-55: 169: 96.83		CHD3_HUMAN (303-1446): 0: 759: 19.68
+	Hs
		241517 H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83		CHD3_HUMAN (303-1446): 0: 759: 19.68
+	Hs
		707612 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		CHD3_HUMAN (303-1446): 0: 759: 19.68
+	Hs
		1087418 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		CHD8_HUMAN (2-1474): 0: 725: 16.46
+	Hs
		1307128 H2B1M_HUMAN (1-126): 5.06e-55: 169: 96.83		CHD8_HUMAN (2-1474): 0: 725: 16.46
+	Hs
		707755 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		CHD8_HUMAN (2-1474): 0: 725: 16.46
+	Hs
		658684 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		SMCA1_HUMAN (369-1372): 0: 700: 20.58
+	Hs
		229415 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		SMCA5_HUMAN (368-1383): 0: 698: 20.75
+	Hs
		229458 H2B1H_HUMAN (1-126): 6.88e-55: 169: 96.83		SMCA5_HUMAN (368-1383): 0: 698: 20.75
+	Hs
		229321 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		SMCA5_HUMAN (368-1383): 0: 698: 20.75
+	Hs
		846990 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		SMCA4_HUMAN (228-1324): 0: 677: 19.90
+	Hs
		1102052 H2B1H_HUMAN (1-126): 6.88e-55: 169: 96.83		ERC6L_HUMAN (482-1007): 6.57e-91: 324: 35.92