Protein: TF3B
Transcription factor IIIB 70 kDa subunit (TFIIIB) (B-related factor 1) (BRF-1)

Gene: TF3B, BRF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 190
UniProt ID: P29056

Gene Ontology (top 5):
GO:0000126 - transcription factor TFIIIB complex
GO:0000994 - RNA polymerase III core binding
GO:0000995 - RNA polymerase III general transcription initiation factor activity
GO:0001006 - RNA polymerase III type 3 promoter sequence-specific DNA binding
GO:0001112 - DNA-templated transcription open complex formation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

561430

TBP
TATA-box-binding protein

14

13

Small-scale

0.983

High

708757

TFC5
Transcription factor TFIIIB component B''

8

2

Small-scale

0.966

High

708702

RPC6
DNA-directed RNA polymerase III subunit RPC6

6

4

Small-scale

0.935

High

647030

RPC2
DNA-directed RNA polymerase III subunit RPC2

4

5

Small-scale

0.893

High

402200

RPC1
DNA-directed RNA polymerase III subunit RPC1

3

5

Small-scale

0.827

High

708746

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

2

3

High-throughput

0.754

High

708705

TFC4
Transcription factor tau 131 kDa subunit

9

5

Small-scale

0.748

High

708759

RPC9
DNA-directed RNA polymerase III subunit RPC9

4

1

Small-scale

0.684

High

708694

RPC3
DNA-directed RNA polymerase III subunit RPC3

4

1

Small-scale

0.680

High

706403

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.618

High

708693

TF3B
Transcription factor IIIB 70 kDa subunit

1

3

High-throughput

0.618

High

381923

H4
Histone H4

2

1

High-throughput

0.584

High

459045

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

7

High-throughput

0.584

High

609181

RPC7
DNA-directed RNA polymerase III subunit RPC7

2

1

High-throughput

0.584

High

632139

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

2

2

High-throughput

0.584

High

632238

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

2

3

High-throughput

0.584

High

645032

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

1

High-throughput

0.584

High

674392

RPC4
DNA-directed RNA polymerase III subunit RPC4

2

1

High-throughput

0.584

High

699980

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

2

5

High-throughput

0.584

High

708711

RPC8
DNA-directed RNA polymerase III subunit RPC8

2

4

High-throughput

0.584

High

708716

RPC5
DNA-directed RNA polymerase III subunit RPC5

2

2

High-throughput

0.584

High

708753

MAF1
Repressor of RNA polymerase III transcription MAF1

2

2

Small-scale

0.584

High

708782

RPC10
DNA-directed RNA polymerase III subunit RPC10

2

6

High-throughput

0.584

High

380999

H2B1
Histone H2B.1

2

3

High-throughput

0.571

High

708774

H3
Histone H3

2

1

High-throughput

0.571

High

526106

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.552

High

708695

TFC1
Transcription factor tau 95 kDa subunit

1

2

Small-scale

0.508

High

150268

RPN13
26S proteasome regulatory subunit RPN13

1

1

High-throughput

0.479

High

154308

MBF1
Multiprotein-bridging factor 1

1

1

High-throughput

0.479

High

366780

IPYR
Inorganic pyrophosphatase

1

1

High-throughput

0.479

High

381436

H2B2
Histone H2B.2

1

3

High-throughput

0.479

High

403393

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

2

High-throughput

0.479

High

419375

H2A1
Histone H2A.1

1

1

High-throughput

0.479

High

444446

DED1
ATP-dependent RNA helicase DED1

1

3

High-throughput

0.479

High

454085

DHE4
NADP-specific glutamate dehydrogenase 1

1

2

High-throughput

0.479

High

486762

CDC16
Anaphase-promoting complex subunit CDC16

1

5

High-throughput

0.479

High

504642

YP13B
Transposon Ty1-PR2 Gag-Pol polyprotein

1

14

High-throughput

0.479

High

547769

NHP6A
Non-histone chromosomal protein 6A

1

4

High-throughput

0.479

High

547856

NHP6B
Non-histone chromosomal protein 6B

1

4

High-throughput

0.479

High

575903

CYPH
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.479

High

585225

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.479

High

590561

HSP26
Heat shock protein 26

1

3

High-throughput

0.479

High

594240

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

7

High-throughput

0.479

High

632317

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

3

High-throughput

0.479

High

637182

PWP1
Periodic tryptophan protein 1

1

6

High-throughput

0.479

High

647716

RFA1
Replication factor A protein 1

1

2

High-throughput

0.479

High

670420

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

675779

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.479

High

676892

SRO9
RNA-binding protein SRO9

1

3

High-throughput

0.479

High

679450

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

692538

NSR1
Nuclear localization sequence-binding protein

1

4

High-throughput

0.479

High

694491

SPT5
Transcription elongation factor SPT5

1

2

High-throughput

0.479

High

708701

RAD23
UV excision repair protein RAD23

1

2

High-throughput

0.479

High

708703

MRT4
Ribosome assembly factor MRT4

1

2

High-throughput

0.479

High

708704

PRS6B
26S proteasome regulatory subunit 6B homolog

1

3

High-throughput

0.479

High

708708

TAF14
Transcription initiation factor TFIID subunit 14

1

5

High-throughput

0.479

High

708709

MDJ1
DnaJ homolog 1, mitochondrial

1

5

High-throughput

0.479

High

708710

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

708712

BDF1
Bromodomain-containing factor 1

1

10

High-throughput

0.479

High

708723

SWC5
SWR1-complex protein 5

1

1

High-throughput

0.479

High

708724

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.479

High

708725

PAF1
RNA polymerase II-associated protein 1

1

1

High-throughput

0.479

High

708726

LEO1
RNA polymerase-associated protein LEO1

1

2

High-throughput

0.479

High

708727

KSP1
Serine/threonine-protein kinase KSP1

1

4

High-throughput

0.479

High

708728

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.479

High

708731

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

708732

RPB11
DNA-directed RNA polymerase II subunit RPB11

1

5

High-throughput

0.479

High

708733

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

5

High-throughput

0.479

High

708735

SMC2
Structural maintenance of chromosomes protein 2

1

4

Small-scale

0.479

High

708738

FHP
Flavohemoprotein

1

4

High-throughput

0.479

High

708739

EXO1
Exodeoxyribonuclease 1

1

2

High-throughput

0.479

High

708740

SNU13
13 kDa ribonucleoprotein-associated protein

1

5

High-throughput

0.479

High

708741

NUG1
Nuclear GTP-binding protein NUG1

1

4

High-throughput

0.479

High

708742

MSRA
Peptide methionine sulfoxide reductase

1

1

High-throughput

0.479

High

708750

NOP2
25S rRNA

1

4

High-throughput

0.479

High

708751

RS29B
Small ribosomal subunit protein uS14B

1

1

High-throughput

0.479

High

708752

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

4

High-throughput

0.479

High

708755

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

1

High-throughput

0.479

High

708756

CSK2B
Casein kinase II subunit beta

1

2

Small-scale

0.479

High

708761

MTNB
Methylthioribulose-1-phosphate dehydratase

1

1

High-throughput

0.479

High

708762

HGH1
Protein HGH1

1

1

High-throughput

0.479

High

708767

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.479

High

708768

NOP13
Nucleolar protein 13

1

1

High-throughput

0.479

High

708769

NOP15
Ribosome biogenesis protein 15

1

2

High-throughput

0.479

High

708770

AF9
Protein AF-9 homolog

1

5

High-throughput

0.479

High

708771

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.479

High

708772

RL15B
Large ribosomal subunit protein eL15B

1

1

High-throughput

0.479

High

708773

ACT
Actin

1

1

High-throughput

0.479

High

708777

VPS72
Vacuolar protein sorting-associated protein 72

1

1

High-throughput

0.479

High

708778

STE20
Serine/threonine-protein kinase STE20

1

3

High-throughput

0.479

High

708779

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

2

High-throughput

0.479

High

708780

GLRX3
Monothiol glutaredoxin-3

1

7

High-throughput

0.479

High

708781

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.479

High

708784

UTP14
U3 small nucleolar RNA-associated protein 14

1

2

High-throughput

0.479

High

708785

POB3
FACT complex subunit POB3

1

1

High-throughput

0.479

High

708786

YM14B
Transposon Ty1-MR2 Gag-Pol polyprotein

1

14

High-throughput

0.479

High

708787

FKBP4
FK506-binding protein 4

1

5

High-throughput

0.479

High

708789

IWS1
Transcription factor SPN1

1

1

High-throughput

0.479

High

708790

CDC73
Cell division control protein 73

1

1

High-throughput

0.479

High

708793

BUD20
Bud site selection protein 20

1

1

High-throughput

0.479

High

708798

RRS1
Regulator of ribosome biosynthesis

1

1

High-throughput

0.479

High

708799

NIP7
60S ribosome subunit biogenesis protein NIP7

1

1

High-throughput

0.479

High

708800

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.479

High

708801

SAS10
Something about silencing protein 10

1

1

High-throughput

0.479

High

708802

YRA1
RNA annealing protein YRA1

1

3

High-throughput

0.479

High

708804

TFC7
Transcription factor tau 55 kDa subunit

1

1

High-throughput

0.479

High

708806

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.479

High

708809

CMR1
DNA damage-binding protein CMR1

1

3

High-throughput

0.479

High

708811

NCB2
Negative cofactor 2 complex subunit beta

1

2

High-throughput

0.479

High

461019

MOD5
tRNA dimethylallyltransferase

1

0

Small-scale

0.458

High

708698

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

Small-scale

0.458

High

708706

TFC3
Transcription factor tau 138 kDa subunit

1

0

Small-scale

0.458

High

708776

YKZ1
Uncharacterized protein YKR011C

1

0

High-throughput

0.458

High

708788

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

523273

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

708696

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.445

High

708717

SET3
SET domain-containing protein 3

1

3

High-throughput

0.445

High

708764

RL4B
Large ribosomal subunit protein uL4B

1

2

High-throughput

0.445

High

708807

CAF1A
Chromatin assembly factor 1 subunit A

1

3

High-throughput

0.445

High

361967

HIS1
ATP phosphoribosyltransferase

1

1

High-throughput

0.437

High

364964

KPYK1
Pyruvate kinase 1

1

2

High-throughput

0.437

High

365577

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.437

High

367712

ENO1
Enolase 1

1

4

High-throughput

0.437

High

367918

ENO2
Enolase 2

1

4

High-throughput

0.437

High

368419

TPIS
Triosephosphate isomerase

1

1

High-throughput

0.437

High

368615

PMG1
Phosphoglycerate mutase 1

1

3

High-throughput

0.437

High

383097

RLA4
Large ribosomal subunit protein P2B

1

2

High-throughput

0.437

High

386608

TBB
Tubulin beta chain

1

1

High-throughput

0.437

High

417046

VDAC1
Non-selective voltage-gated ion channel 1

1

1

High-throughput

0.437

High

427549

RLA1
Large ribosomal subunit protein P1A

1

3

High-throughput

0.437

High

434532

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.437

High

439105

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

1

High-throughput

0.437

High

450711

KAD2
Adenylate kinase

1

2

High-throughput

0.437

High

452846

ATPA
ATP synthase subunit alpha, mitochondrial

1

4

High-throughput

0.437

High

454616

PROF
Profilin

1

1

High-throughput

0.437

High

504083

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

511640

RS23B
Small ribosomal subunit protein uS12B

1

2

High-throughput

0.437

High

528803

RLA3
Large ribosomal subunit protein P1B

1

3

High-throughput

0.437

High

554889

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.437

High

578985

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.437

High

585597

STI1
Heat shock protein STI1

1

5

High-throughput

0.437

High

592068

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.437

High

596801

ODPX
Pyruvate dehydrogenase complex protein X component, mitochondrial

1

4

High-throughput

0.437

High

605290

CAP
Adenylyl cyclase-associated protein

1

1

High-throughput

0.437

High

610109

PDI
Protein disulfide-isomerase

1

2

High-throughput

0.437

High

673551

NLE1
Ribosome assembly protein 4

1

3

High-throughput

0.437

High

688725

RFA2
Replication factor A protein 2

1

2

High-throughput

0.437

High

708697

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

5

High-throughput

0.437

High

708699

SPT16
FACT complex subunit SPT16

1

4

High-throughput

0.437

High

708700

VATD
V-type proton ATPase subunit D

1

1

High-throughput

0.437

High

708707

EDE1
EH domain-containing and endocytosis protein 1

1

3

High-throughput

0.437

High

708714

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.437

High

708715

EBP2
rRNA-processing protein EBP2

1

1

High-throughput

0.437

High

708718

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

2

High-throughput

0.437

High

708719

VRP1
Verprolin

1

3

High-throughput

0.437

High

708720

AHP1
Peroxiredoxin AHP1

1

1

High-throughput

0.437

High

708721

PDX3
Pyridoxamine 5'-phosphate oxidase

1

1

High-throughput

0.437

High

708722

ARL1
ADP-ribosylation factor-like protein 1

1

4

High-throughput

0.437

High

708729

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.437

High

708730

RPF1
Ribosome production factor 1

1

2

High-throughput

0.437

High

708734

BFR1
Nuclear segregation protein BFR1

1

1

High-throughput

0.437

High

708736

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.437

High

708737

TCPD
T-complex protein 1 subunit delta

1

5

High-throughput

0.437

High

708743

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

1

High-throughput

0.437

High

708744

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

1

High-throughput

0.437

High

708745

MPM1
Mitochondrial peculiar membrane protein 1

1

1

High-throughput

0.437

High

708747

6P21
6-phosphofructo-2-kinase 1

1

4

High-throughput

0.437

High

708749

RLP7
Ribosome biogenesis protein RLP7

1

3

High-throughput

0.437

High

708754

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.437

High

708758

NET1
Nucleolar protein NET1

1

2

High-throughput

0.437

High

708760

TCPQ
T-complex protein 1 subunit theta

1

2

High-throughput

0.437

High

708763

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.437

High

708765

MLC1
Myosin light chain 1

1

1

High-throughput

0.437

High

708766

TWF1
Twinfilin-1

1

2

High-throughput

0.437

High

708783

TAP42
Type 2A phosphatase-associated protein 42

1

1

High-throughput

0.437

High

708791

SSK1
Osmolarity two-component system protein SSK1

1

2

High-throughput

0.437

High

708792

RLP24
Ribosome biogenesis protein RLP24

1

3

High-throughput

0.437

High

708794

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

3

High-throughput

0.437

High

708795

BRX1
Ribosome biogenesis protein BRX1

1

7

High-throughput

0.437

High

708796

UTP16
U3 small nucleolar RNA-associated protein 16

1

1

High-throughput

0.437

High

708797

RPN8
26S proteasome regulatory subunit RPN8

1

1

High-throughput

0.437

High

708803

HSP42
Heat shock protein 42

1

3

High-throughput

0.437

High

708805

PAA1
Polyamine N-acetyltransferase 1

1

1

High-throughput

0.437

High

708808

ARP6
Actin-like protein ARP6

1

3

High-throughput

0.437

High

708810

RL21B
Large ribosomal subunit protein eL21B

1

2

High-throughput

0.437

High

394316

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.407

High

708713

OSH1
Oxysterol-binding protein homolog 1

1

3

High-throughput

0.407

High

708748

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

3

High-throughput

0.407

High

708775

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

14

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025