HitPredict

Interactor 1: ABCD1 (P33897)
ATP-binding cassette sub-family D member 1 (EC 3.1.2.-) (EC 7.6.2.-) (Adrenoleukodystrophy protein) (ALDP)
Gene: ABCD1

Interactor 2: ABCD2 (Q9UBJ2)
ATP-binding cassette sub-family D member 2 (EC 3.1.2.-) (EC 7.6.2.-) (Adrenoleukodystrophy-like 1) (Adrenoleukodystrophy-related protein) (hALDR)
Gene: ABCD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 10551832, 24658140
Identification Methods two hybrid, ubiquitin reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ABC_membrane_2~ABC_membrane_2, ABC_membrane_2~ABC_tran, ABC_tran~ABC_tran
Common GO terms GO:0000038 - very long-chain fatty acid metabolic process
GO:0005324 - long-chain fatty acid transmembrane transporter activity
GO:0005524 - ATP binding
GO:0005777 - peroxisome
GO:0005778 - peroxisomal membrane
and 16 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 745
Hs

1 740
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Mt
+ Hs
+ Hs
+ Sc
+ Sc
+ Rn
+ Se

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024