HitPredict

Interactor 1: MCM4 (P33991)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)
Gene: MCM4

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 863 Hs			1 127
+	Hs
		708456 MCM4_HUMAN (1-863): 0: 952: 100.00		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		241460 MCM4_HUMAN (1-863): 0: 952: 100.00		H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25
+	Hs
		707531 MCM4_HUMAN (1-863): 0: 952: 100.00		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		708414 MCM4_HUMAN (1-863): 0: 952: 100.00		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		832673 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B1M_HUMAN (1-127): 6.74e-55: 169: 84.25
+	Hs
		832512 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B2F_HUMAN (5-127): 1.83e-54: 168: 85.37
+	Hs
		420814 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B1J_HUMAN (1-127): 4.39e-54: 167: 85.04
+	Hs
		617935 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B1O_HUMAN (5-127): 3.41e-54: 167: 86.18
+	Hs
		832497 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		241476 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25
+	Hs
		707553 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		832280 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B1D_HUMAN (1-127): 1.37e-53: 166: 85.04
+	Hs
		832322 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		832624 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37
+	Hs
		832671 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B1N_HUMAN (1-127): 1.22e-53: 166: 85.83
+	Hs
		832629 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00
+	Hs
		832674 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B1L_HUMAN (1-127): 1.35e-52: 163: 85.83
+	Hs
		832577 MCM2_HUMAN (2-839): 0: 762: 27.95		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Sc
		355817 MCM4_YEAST (1-862): 0: 745: 41.83		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36
+	Hs
		241461 MCM5_HUMAN (133-846): 0: 698: 30.23		H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25