Interactor 1: MCM4 (P33991)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)
Gene: MCM4

Interactor 2: SLD5 (Q9BRT9)
DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]
Gene: GINS4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34195792
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~Sld5, MCM_N~Sld5
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006268 - DNA unwinding involved in DNA replication
GO:0071162 - CMG complex
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 863
Hs

1 223
+ Dm
+ Hs
+ Mm
+ Hs
+ Sc
+ Mm
+ Hs
+ Dm
+ Mm
+ Hs
+ Sc
+ Sc
+ Dm

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Last updated: 15 Jul 2024