HitPredict

Interactor 1: MCM7 (P33993)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Gene: MCM7

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27248496
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006974 - DNA damage response
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 719 Hs			1 626
+	Hs
		708771 MCM5_HUMAN (6-716): 0: 682: 27.61		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		708519 MCM4_HUMAN (5-700): 0: 636: 31.52		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		708987 MCM7_HUMAN (1-719): 0: 786: 100.00		COP1_HUMAN (154-619): 7.6e-71: 245: 14.96
+	Hs
		709001 MCM7_HUMAN (1-719): 0: 786: 100.00		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Hs
		708826 MCM7_HUMAN (1-719): 0: 786: 100.00		LIS1_HUMAN (118-478): 6.33e-51: 183: 9.73
+	Hs
		708707 MCM5_HUMAN (6-716): 0: 682: 27.61		COP1_HUMAN (154-619): 7.6e-71: 245: 14.96
+	Hs
		709008 MCM7_HUMAN (1-719): 0: 786: 100.00		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Sc
		675577 MCM4_YEAST (7-703): 0: 658: 29.69		CMR1_YEAST (159-623): 1.38e-74: 249: 23.50
+	Sc
		744802 MCM7_YEAST (2-719): 0: 643: 45.41		CMR1_YEAST (159-623): 1.38e-74: 249: 23.50
+	Hs
		832625 MCM2_HUMAN (8-690): 0: 643: 28.13		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Sc
		859036 MCM6_YEAST (9-704): 0: 616: 29.69		CMR1_YEAST (159-623): 1.38e-74: 249: 23.50
+	Hs
		1055604 MCM6_HUMAN (3-715): 0: 623: 28.05		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Hs
		708496 MCM4_HUMAN (5-700): 0: 636: 31.52		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Hs
		832406 MCM2_HUMAN (8-690): 0: 643: 28.13		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55