HitPredict

Interactor 1: FAK1 (P34152)
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)
Gene: Ptk2

Interactor 2: GRB2 (Q60631)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.695

The method score is based on:

Property Details
Experiments 7997267, 16298995
Identification Methods experimental interaction detection, anti bait coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005938 - cell cortex
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0044877 - protein-containing complex binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1052
Mm

1 217
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024