Protein: GATA3
Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3)

Gene: GATA3
Organism: Homo sapiens
Interactions: 203
UniProt ID: P23771

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

620454

RBTN1
Rhombotin-1

2

12

Small-scale

0.768

High

620565

MTA3
Metastasis-associated protein MTA3

1

20

Small-scale

0.748

High

620497

HDAC1
Histone deacetylase 1

3

15

Small-scale

0.667

High

620541

HDAC2
Histone deacetylase 2

3

15

Small-scale

0.667

High

232004

KDM1A
Lysine-specific histone demethylase 1A

3

12

Small-scale

0.660

High

177196

HDAC3
Histone deacetylase 3

2

15

Small-scale

0.641

High

620544

CBP
CREB-binding protein

2

20

Small-scale

0.634

High

620548

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

2

3

High-throughput

0.618

High

620294

GATA2
Endothelial transcription factor GATA-2

1

13

High-throughput

0.618

High

620453

RBTN2
Rhombotin-2

1

11

Small-scale

0.618

High

620588

TRPS1
Zinc finger transcription factor Trps1

1

15

High-throughput

0.618

High

368997

ESR1
Estrogen receptor

2

14

Small-scale

0.588

High

620561

CIC
Protein capicua homolog

2

18

High-throughput

0.584

High

620579

TF7L2
Transcription factor 7-like 2

2

18

Small-scale

0.584

High

620591

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

2

1

Small-scale

0.584

High

620592

RCOR1
REST corepressor 1

2

20

Small-scale

0.584

High

620511

PKHG4
Puratrophin-1

2

0

High-throughput

0.580

High

620558

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

3

Small-scale

0.579

High

443130

NFIC
Nuclear factor 1 C-type

1

10

High-throughput

0.578

High

620492

NFIA
Nuclear factor 1 A-type

1

11

High-throughput

0.578

High

620505

HIF1A
Hypoxia-inducible factor 1-alpha

1

3

Small-scale

0.578

High

620452

PSA3
Proteasome subunit alpha type-3

1

2

High-throughput

0.573

High

568178

TAL1
T-cell acute lymphocytic leukemia protein 1

2

9

Small-scale

0.571

High

620471

FOXA1
Hepatocyte nuclear factor 3-alpha

2

13

Small-scale

0.571

High

135077

NFIB
Nuclear factor 1 B-type

1

9

High-throughput

0.561

High

434949

SP1
Transcription factor Sp1

1

11

Small-scale

0.561

High

620550

FBXW7
F-box/WD repeat-containing protein 7

1

6

Small-scale

0.561

High

620593

TBX21
T-box transcription factor TBX21

1

6

Small-scale

0.554

High

66984

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.553

High

620510

KR132
Keratin-associated protein 13-2

2

1

High-throughput

0.553

High

500355

RARB
Retinoic acid receptor beta

1

13

High-throughput

0.541

High

620568

TRI55
Tripartite motif-containing protein 55

1

4

High-throughput

0.541

High

161964

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

5

High-throughput

0.536

High

297458

TOX4
TOX high mobility group box family member 4

1

12

High-throughput

0.536

High

620465

NU153
Nuclear pore complex protein Nup153

1

4

High-throughput

0.536

High

620480

TOP2B
DNA topoisomerase 2-beta

1

2

High-throughput

0.536

High

620483

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

2

High-throughput

0.536

High

620506

SMU1
WD40 repeat-containing protein SMU1

1

11

High-throughput

0.536

High

620583

PK1IP
p21-activated protein kinase-interacting protein 1

1

6

High-throughput

0.536

High

411599

LCK
Tyrosine-protein kinase Lck

1

0

High-throughput

0.518

High

620597

HDAC5
Histone deacetylase 5

1

20

Small-scale

0.515

High

609178

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.515

High

620455

CLAT
Choline O-acetyltransferase

1

1

High-throughput

0.515

High

309364

MBD4
Methyl-CpG-binding domain protein 4

1

0

High-throughput

0.513

High

620524

STX12
Syntaxin-12

1

0

High-throughput

0.513

High

620533

LEMD2
LEM domain-containing protein 2

1

0

High-throughput

0.513

High

620571

ZN768
Zinc finger protein 768

1

0

High-throughput

0.513

High

620573

CBX8
Chromobox protein homolog 8

1

0

High-throughput

0.513

High

620578

RM40
Large ribosomal subunit protein mL40

1

0

High-throughput

0.513

High

620576

GCM1
Chorion-specific transcription factor GCMa

1

0

Small-scale

0.512

High

487901

RARA
Retinoic acid receptor alpha

1

13

Small-scale

0.505

High

568547

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

3

Small-scale

0.501

High

572539

SPI1
Transcription factor PU.1

1

14

Small-scale

0.501

High

620451

CDK2
Cyclin-dependent kinase 2

1

3

Small-scale

0.501

High

620503

MK14
Mitogen-activated protein kinase 14

1

6

Small-scale

0.501

High

365152

FRIH
Ferritin heavy chain

1

1

High-throughput

0.500

High

386111

P53
Cellular tumor antigen p53

1

1

High-throughput

0.500

High

620459

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.500

High

620467

EMD
Emerin

1

2

High-throughput

0.500

High

620488

LG3BP
Galectin-3-binding protein

1

1

High-throughput

0.500

High

620502

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.500

High

620512

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

1

High-throughput

0.500

High

620545

RAD50
DNA repair protein RAD50

1

2

High-throughput

0.500

High

620557

DCAF5
DDB1- and CUL4-associated factor 5

1

4

High-throughput

0.500

High

620574

MOV10
Helicase MOV-10

1

1

High-throughput

0.500

High

297035

TOM70
Mitochondrial import receptor subunit TOM70

1

2

High-throughput

0.489

High

619195

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

1

High-throughput

0.489

High

620589

NB5R1
NADH-cytochrome b5 reductase 1

1

1

High-throughput

0.489

High

328494

MBD3
Methyl-CpG-binding domain protein 3

1

5

Small-scale

0.484

High

620551

TRI63
E3 ubiquitin-protein ligase TRIM63

1

1

High-throughput

0.481

High

620566

REPI1
Replication initiator 1

1

0

Small-scale

0.480

High

620466

MRE11
Double-strand break repair protein MRE11

1

0

High-throughput

0.479

High

620521

PEG10
Retrotransposon-derived protein PEG10

1

0

High-throughput

0.479

High

131693

BCL9
B-cell CLL/lymphoma 9 protein

1

15

High-throughput

0.479

High

146159

ARI1A
AT-rich interactive domain-containing protein 1A

1

15

High-throughput

0.479

High

152590

KMT2D
Histone-lysine N-methyltransferase 2D

1

16

High-throughput

0.479

High

164186

ZN609
Zinc finger protein 609

1

6

High-throughput

0.479

High

167136

ZN536
Zinc finger protein 536

1

5

High-throughput

0.479

High

183066

KDM6A
Lysine-specific demethylase 6A

1

7

High-throughput

0.479

High

215586

AKAP8
A-kinase anchor protein 8

1

2

High-throughput

0.479

High

245561

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

9

High-throughput

0.479

High

261405

NCOR1
Nuclear receptor corepressor 1

1

17

High-throughput

0.479

High

263521

PR40A
Pre-mRNA-processing factor 40 homolog A

1

4

High-throughput

0.479

High

300400

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

3

High-throughput

0.479

High

304586

SCAF4
SR-related and CTD-associated factor 4

1

17

High-throughput

0.479

High

321706

WIZ
Protein Wiz

1

3

High-throughput

0.479

High

379027

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.479

High

396847

IL4
Interleukin-4

1

1

Small-scale

0.479

High

414439

PRGR
Progesterone receptor

1

11

Small-scale

0.479

High

486744

MYB
Transcriptional activator Myb

1

2

Small-scale

0.479

High

487137

ANDR
Androgen receptor

1

11

Small-scale

0.479

High

550319

ZEP1
Zinc finger protein 40

1

4

High-throughput

0.479

High

569200

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

620457

BMI1
Polycomb complex protein BMI-1

1

16

Small-scale

0.479

High

620464

CEBPD
CCAAT/enhancer-binding protein delta

1

5

Small-scale

0.479

High

620468

SMCA2
Probable global transcription activator SNF2L2

1

20

High-throughput

0.479

High

620472

HDAC4
Histone deacetylase 4

1

20

Small-scale

0.479

High

620474

DCAF7
DDB1- and CUL4-associated factor 7

1

9

High-throughput

0.479

High

620475

SKP1
S-phase kinase-associated protein 1

1

1

High-throughput

0.479

High

620476

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.479

High

620479

SATB1
DNA-binding protein SATB1

1

4

High-throughput

0.479

High

620481

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

620482

TLE3
Transducin-like enhancer protein 3

1

17

High-throughput

0.479

High

620484

SUH
Recombining binding protein suppressor of hairless

1

3

High-throughput

0.479

High

620485

RING1
E3 ubiquitin-protein ligase RING1

1

18

High-throughput

0.479

High

620486

SOX4
Transcription factor SOX-4

1

20

Small-scale

0.479

High

620487

TLE5
TLE family member 5

1

10

High-throughput

0.479

High

620490

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.479

High

620491

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

3

High-throughput

0.479

High

620493

FOXC1
Forkhead box protein C1

1

15

High-throughput

0.479

High

620494

TADBP
TAR DNA-binding protein 43

1

4

High-throughput

0.479

High

620501

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

Small-scale

0.479

High

620509

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

4

High-throughput

0.479

High

620514

RBM20
RNA-binding protein 20

1

4

High-throughput

0.479

High

620515

BEND3
BEN domain-containing protein 3

1

3

High-throughput

0.479

High

620517

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

15

High-throughput

0.479

High

620518

BCOR
BCL-6 corepressor

1

3

High-throughput

0.479

High

620520

PAXI1
PAX-interacting protein 1

1

7

High-throughput

0.479

High

620522

PB1
Protein polybromo-1

1

15

High-throughput

0.479

High

620523

ZFHX4
Zinc finger homeobox protein 4

1

5

High-throughput

0.479

High

620525

ARI3B
AT-rich interactive domain-containing protein 3B

1

18

High-throughput

0.479

High

620526

SUGP2
SURP and G-patch domain-containing protein 2

1

2

High-throughput

0.479

High

620527

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

1

High-throughput

0.479

High

620528

YAF2
YY1-associated factor 2

1

3

High-throughput

0.479

High

620529

RAVR1
Ribonucleoprotein PTB-binding 1

1

4

High-throughput

0.479

High

620530

RYBP
RING1 and YY1-binding protein

1

3

High-throughput

0.479

High

620531

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

3

High-throughput

0.479

High

620534

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

620535

KDM2B
Lysine-specific demethylase 2B

1

2

High-throughput

0.479

High

620536

MORC4
MORC family CW-type zinc finger protein 4

1

2

High-throughput

0.479

High

620538

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

4

High-throughput

0.479

High

620539

FOG2
Zinc finger protein ZFPM2

1

12

High-throughput

0.479

High

620542

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

620543

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

620546

SMRC1
SWI/SNF complex subunit SMARCC1

1

19

High-throughput

0.479

High

620547

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

10

High-throughput

0.479

High

620549

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

2

High-throughput

0.479

High

620552

FUBP1
Far upstream element-binding protein 1

1

6

High-throughput

0.479

High

620553

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

8

High-throughput

0.479

High

620554

ZN503
Zinc finger protein 503

1

3

High-throughput

0.479

High

620555

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

7

High-throughput

0.479

High

620556

FUBP3
Far upstream element-binding protein 3

1

6

High-throughput

0.479

High

620559

ZFR
Zinc finger RNA-binding protein

1

3

High-throughput

0.479

High

620560

QKI
KH domain-containing RNA-binding protein QKI

1

2

High-throughput

0.479

High

620562

RING2
E3 ubiquitin-protein ligase RING2

1

17

High-throughput

0.479

High

620563

ARI3A
AT-rich interactive domain-containing protein 3A

1

18

High-throughput

0.479

High

620564

PCGF1
Polycomb group RING finger protein 1

1

16

High-throughput

0.479

High

620569

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

10

High-throughput

0.479

High

620570

FOXP3
Forkhead box protein P3

1

16

Small-scale

0.479

High

620572

ZN703
Zinc finger protein 703

1

7

High-throughput

0.479

High

620577

HM20A
High mobility group protein 20A

1

19

High-throughput

0.479

High

620581

RBM12
RNA-binding protein 12

1

5

High-throughput

0.479

High

620584

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

17

High-throughput

0.479

High

620585

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

1

High-throughput

0.479

High

620586

RCOR3
REST corepressor 3

1

20

High-throughput

0.479

High

620590

SIX4
Homeobox protein SIX4

1

6

High-throughput

0.479

High

620594

PRR12
Proline-rich protein 12

1

11

High-throughput

0.479

High

620596

SATB2
DNA-binding protein SATB2

1

4

High-throughput

0.479

High

620598

ZN281
Zinc finger protein 281

1

3

High-throughput

0.479

High

620599

NCOR2
Nuclear receptor corepressor 2

1

18

High-throughput

0.479

High

620600

NCOA3
Nuclear receptor coactivator 3

1

5

High-throughput

0.479

High

620508

KRA63
Keratin-associated protein 6-3

1

1

High-throughput

0.470

High

620456

IL13
Interleukin-13

1

0

Small-scale

0.458

High

620460

BRCA1
Breast cancer type 1 susceptibility protein

1

0

Small-scale

0.458

High

620463

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.458

High

620470

AF17
Protein AF-17

1

0

High-throughput

0.458

High

620478

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

620516

ZN746
Zinc finger protein 746

1

0

High-throughput

0.458

High

620532

ZN709
Zinc finger protein 709

1

0

High-throughput

0.458

High

620537

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

281148

RL1D1
Ribosomal L1 domain-containing protein 1

1

1

High-throughput

0.457

High

364830

FRIL
Ferritin light chain

1

1

High-throughput

0.457

High

499537

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.457

High

153572

ANM5
Protein arginine N-methyltransferase 5

1

1

Small-scale

0.445

High

231205

ZEB2
Zinc finger E-box-binding homeobox 2

1

3

Small-scale

0.445

High

345331

FOS
Protein c-Fos

1

1

Small-scale

0.445

High

431546

HS90A
Heat shock protein HSP 90-alpha

1

3

Small-scale

0.445

High

530783

RARG
Retinoic acid receptor gamma

1

13

Small-scale

0.445

High

620461

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

3

Small-scale

0.445

High

620469

KIF11
Kinesin-like protein KIF11

1

1

Small-scale

0.445

High

620489

RBBP4
Histone-binding protein RBBP4

1

10

Small-scale

0.445

High

620499

STK38
Serine/threonine-protein kinase 38

1

3

Small-scale

0.445

High

620540

AP2C
Transcription factor AP-2 gamma

1

1

Small-scale

0.445

High

620498

GSE1
Genetic suppressor element 1

1

2

High-throughput

0.437

High

620513

PRC2B
Protein PRRC2B

1

12

High-throughput

0.437

High

620575

FBSL
Fibrosin-1-like protein

1

3

High-throughput

0.437

High

620500

JHD2C
Probable JmjC domain-containing histone demethylation protein 2C

1

0

Small-scale

0.426

High

620519

UBR3
E3 ubiquitin-protein ligase UBR3

1

0

Small-scale

0.426

High

620582

SDA1
Protein SDA1 homolog

1

0

Small-scale

0.426

High

620473

KR121
Keratin-associated protein 12-1

2

0

High-throughput

0.316

High

620507

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

620458

ACTN2
Alpha-actinin-2

1

0

High-throughput

0.299

High

620477

RT05
Small ribosomal subunit protein uS5m

1

0

High-throughput

0.279

Low

620496

NNTM
NAD(P) transhydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

620504

FSCN1
Fascin

1

0

High-throughput

0.279

Low

620567

RM09
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.279

Low

620580

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.279

Low

620587

ATX10
Ataxin-10

1

0

High-throughput

0.261

Low

620462

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.249

Low

229627

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

0

Small-scale

0.232

Low

372995

VTNC
Vitronectin

1

0

Small-scale

0.232

Low

620495

MMRN1
Multimerin-1

1

0

Small-scale

0.232

Low

620595

LORF1
LINE-1 retrotransposable element ORF1 protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024