HitPredict

Interactor 1: RGS1 (P34295)
Regulator of G-protein signaling rgs-1
Gene: rgs-1

Interactor 2: GNAO (P51875)
Guanine nucleotide-binding protein G(o) subunit alpha
Gene: goa-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	10950865
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	G-alpha~RGS
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 201 Ce			1 354
+	Hs
		277782 RGS9_HUMAN (5-185): 6.17e-67: 218: 29.28		GNAO_HUMAN (1-354): 2.13e-174: 490: 82.20
+	Hs
		283160 RGS20_HUMAN (13-166): 3.75e-61: 196: 53.25		GNAO_HUMAN (1-354): 2.13e-174: 490: 82.20
+	Hs
		391357 RGS3_HUMAN (11-165): 3.45e-60: 204: 34.59		GNAI2_HUMAN (1-354): 1.57e-171: 482: 68.17
+	Hs
		444692 RGS3_HUMAN (11-165): 3.45e-60: 204: 34.59		GNAI3_HUMAN (1-354): 2.32e-169: 477: 69.86
+	Hs
		283183 RGS20_HUMAN (13-166): 3.75e-61: 196: 53.25		GNAI1_HUMAN (1-354): 3.13e-172: 484: 69.86
+	Hs
		158608 RGS12_HUMAN (26-197): 6.49e-57: 195: 27.53		GNAI1_HUMAN (1-354): 3.13e-172: 484: 69.86
+	Hs
		283156 RGS20_HUMAN (13-166): 3.75e-61: 196: 53.25		GNAI2_HUMAN (1-354): 1.57e-171: 482: 68.17
+	Hs
		158597 RGS12_HUMAN (26-197): 6.49e-57: 195: 27.53		GNAI2_HUMAN (1-354): 1.57e-171: 482: 68.17
+	Hs
		444693 RGS7_HUMAN (7-187): 1.36e-60: 198: 31.49		GNAI3_HUMAN (1-354): 2.32e-169: 477: 69.86
+	Hs
		926720 RGS18_HUMAN (2-173): 4.52e-61: 191: 32.95		GNAI1_HUMAN (1-354): 3.13e-172: 484: 69.86
+	Hs
		207505 RGS14_HUMAN (10-192): 2.03e-57: 191: 28.50		GNAI2_HUMAN (1-354): 1.57e-171: 482: 68.17
+	Hs
		391473 RGS18_HUMAN (2-173): 4.52e-61: 191: 32.95		GNAI2_HUMAN (1-354): 1.57e-171: 482: 68.17
+	Hs
		158599 RGS12_HUMAN (26-197): 6.49e-57: 195: 27.53		GNAI3_HUMAN (1-354): 2.32e-169: 477: 69.86
+	Bt
		221230 RGS9_BOVIN (5-185): 2.54e-68: 218: 28.73		GNAT1_BOVIN (1-354): 1.66e-159: 452: 58.03
+	Hs
		444800 RGS18_HUMAN (2-173): 4.52e-61: 191: 32.95		GNAI3_HUMAN (1-354): 2.32e-169: 477: 69.86
+	Hs
		834946 RGS7_HUMAN (7-187): 1.36e-60: 198: 31.49		GNAQ_HUMAN (1-353): 3.95e-163: 461: 48.59
+	Hs
		670435 RGS3_HUMAN (11-165): 3.45e-60: 204: 34.59		GNA11_HUMAN (1-353): 1.08e-158: 450: 48.02
+	Hs
		837653 RGS18_HUMAN (2-173): 4.52e-61: 191: 32.95		GNAQ_HUMAN (1-353): 3.95e-163: 461: 48.59
+	Hs
		580410 RGS7_HUMAN (7-187): 1.36e-60: 198: 31.49		GNAZ_HUMAN (1-353): 1.44e-154: 440: 59.89
+	Hs
		283162 RGS20_HUMAN (13-166): 3.75e-61: 196: 53.25		GNAZ_HUMAN (1-353): 1.44e-154: 440: 59.89