Interactor 1: GLYC (P34896)
Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)
Gene: SHMT1
Interactor 2: GLYC (P34896)
Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)
Gene: SHMT1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.74 | 1.00 | 0.861 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 32296183, unassigned1304 |
| Identification Methods | two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SHMT~SHMT |
| Common GO terms | GO:0000900 - mRNA regulatory element binding translation repressor activity GO:0004372 - glycine hydroxymethyltransferase activity GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005739 - mitochondrion and 22 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
