HitPredict

Interactor 1: HS71L (P34931)
Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom) (Heat shock protein family A member 1L)
Gene: HSPA1L

Interactor 2: BAG5 (Q9UL15)
BAG family molecular chaperone regulator 5 (BAG-5) (Bcl-2-associated athanogene 5)
Gene: BAG5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAG~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 641 Hs			1 447
+	Hs
		564206 HSP76_HUMAN (1-641): 0: 957: 79.47		BAG5_HUMAN (1-447): 0: 752: 100.00
+	Hs
		1120596 Q53FC7_HUMAN (1-641): 0: 952: 79.01		BAG5_HUMAN (1-447): 0: 752: 100.00
+	Mm
		571863 HS71B_MOUSE (4-641): 0: 945: 86.90		BAG5_MOUSE (1-447): 0: 758: 91.28
+	Mm
		926151 HSP7C_MOUSE (4-615): 0: 945: 84.97		BAG5_MOUSE (1-447): 0: 758: 91.28
+	Hs
		504937 HSP7C_HUMAN (4-615): 0: 946: 84.80		BAG5_HUMAN (1-447): 0: 752: 100.00
+	Hs
		314010 HS71L_HUMAN (1-641): 0: 977: 100.00		BAG4_HUMAN (363-441): 3.44e-30: 123: 44.30
+	Hs
		324256 HS71L_HUMAN (1-641): 0: 977: 100.00		BAG3_HUMAN (361-442): 2.06e-28: 119: 44.71
+	Hs
		314001 HSP76_HUMAN (1-641): 0: 957: 79.47		BAG4_HUMAN (363-441): 3.44e-30: 123: 44.30
+	Hs
		324216 HSP76_HUMAN (1-641): 0: 957: 79.47		BAG3_HUMAN (361-442): 2.06e-28: 119: 44.71
+	Hs
		314060 Q53FC7_HUMAN (1-641): 0: 952: 79.01		BAG4_HUMAN (363-441): 3.44e-30: 123: 44.30
+	Hs
		324435 Q53FC7_HUMAN (1-641): 0: 952: 79.01		BAG3_HUMAN (361-442): 2.06e-28: 119: 44.71
+	Hs
		313996 HSP7C_HUMAN (4-615): 0: 946: 84.80		BAG4_HUMAN (363-441): 3.44e-30: 123: 44.30
+	Mm
		571864 HS71B_MOUSE (4-641): 0: 945: 86.90		BAG4_MOUSE (363-441): 1.06e-29: 122: 44.30
+	Hs
		324195 HSP7C_HUMAN (4-615): 0: 946: 84.80		BAG3_HUMAN (361-442): 2.06e-28: 119: 44.71
+	Mm
		571868 HS71B_MOUSE (4-641): 0: 945: 86.90		BAG3_MOUSE (361-442): 1.12e-27: 117: 45.88
+	Mm
		926166 HSP7C_MOUSE (4-615): 0: 945: 84.97		BAG3_MOUSE (361-442): 1.12e-27: 117: 45.88
+	Hs
		324190 HS71A_HUMAN (1-641): 0: 938: 88.80		BAG3_HUMAN (361-442): 2.06e-28: 119: 44.71
+	Dm
		65599 HSP71_DROME (8-641): 0: 939: 73.38		A8JNS4_DROME (9-87): 2.89e-13: 73.9: 35.44
+	Dm
		947905 HSP70_DROME (8-641): 0: 939: 73.38		Q9VU81_DROME (9-87): 2.8e-13: 73.9: 35.44
+	Dm
		65608 HSP74_DROME (8-641): 0: 938: 73.64		A8JNS4_DROME (9-87): 2.89e-13: 73.9: 35.44