HitPredict

Interactor 1: PROF2 (P35080)
Profilin-2 (Profilin II)
Gene: PFN2

Interactor 2: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	15383276, 32814053
Identification Methods	pull down, two hybrid, validated two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 3142
+	Hs
		430086 PROF1_HUMAN (1-140): 4.25e-74: 219: 61.43		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Mm
		103249 PROF2_MOUSE (1-140): 3.3e-76: 224: 99.29		G3X9H5_MOUSE (81-3142): 0: 5479: 91.19