HitPredict

Interactor 1: SC61G (P35179)
Protein transport protein SSS1 (Sec61 complex subunit SSS1) (Sec61 complex subunit gamma) (Ssh1 complex subunit SSS1) (Ssh1 complex subunit gamma)
Gene: SSS1

Interactor 2: SSH1 (P38353)
Sec sixty-one protein homolog (Ssh1 complex subunit SSH1) (Ssh1 complex subunit alpha)
Gene: SSH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

The method score is based on:

Property	Details
Experiments	23497013, 8612571
Identification Methods	protein complementation assay, anti bait coimmunoprecipitation, affinity chromatography technology
Interaction Type	direct interaction, association, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Plug_translocon~SecE, SecE~SecY
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005784 - Sec61 translocon complex GO:0005789 - endoplasmic reticulum membrane GO:0006614 - SRP-dependent cotranslational protein targeting to membrane GO:0006616 - SRP-dependent cotranslational protein targeting to membrane, translocation and 3 others more... GO:0008320 - protein transmembrane transporter activity GO:0031204 - post-translational protein targeting to membrane, translocation GO:0071261 - Ssh1 translocon complex
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	80
Sc

1	490

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024