Protein: CH10
10 kDa heat shock protein, mitochondrial (Hsp10) (10 kDa chaperonin) (Chaperonin 10) (CPN10) (Early-pregnancy factor) (EPF) (Heat shock protein family E member 1)

Gene: CH10, HSPE1
Organism: Homo sapiens
Interactions: 226
UniProt ID: P61604

Gene Ontology (top 5):
GO:0001649 - osteoblast differentiation
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

532496

CH60
60 kDa heat shock protein, mitochondrial

6

7

Small-scale

0.934

High

962920

CH10
10 kDa heat shock protein, mitochondrial

3

10

High-throughput

0.827

High

962958

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

1

High-throughput

0.754

High

279721

CISY
Citrate synthase, mitochondrial

3

3

High-throughput

0.650

High

828728

MDHM
Malate dehydrogenase, mitochondrial

3

1

High-throughput

0.640

High

619670

VCAM1
Vascular cell adhesion protein 1

2

1

High-throughput

0.601

High

962925

EF1A1
Elongation factor 1-alpha 1

2

0

High-throughput

0.588

High

361197

SODC
Superoxide dismutase [Cu-Zn]

2

0

High-throughput

0.585

High

165030

RPC1
DNA-directed RNA polymerase III subunit RPC1

2

1

High-throughput

0.584

High

348453

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

2

High-throughput

0.584

High

563530

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.576

High

717278

PEBP1
Phosphatidylethanolamine-binding protein 1

2

2

High-throughput

0.571

High

934376

TERA
Transitional endoplasmic reticulum ATPase

2

1

High-throughput

0.571

High

962924

RAC1
Ras-related C3 botulinum toxin substrate 1

2

2

High-throughput

0.571

High

962985

DOCK8
Dedicator of cytokinesis protein 8

2

0

High-throughput

0.547

High

180764

TIF1A
Transcription intermediary factor 1-alpha

1

3

High-throughput

0.536

High

334615

LYPA2
Acyl-protein thioesterase 2

1

1

High-throughput

0.536

High

853963

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

861546

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

1

High-throughput

0.536

High

962989

NEK7
Serine/threonine-protein kinase Nek7

1

1

High-throughput

0.536

High

963008

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.536

High

963015

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

1

High-throughput

0.536

High

371636

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.533

High

962936

SOS2
Son of sevenless homolog 2

2

1

High-throughput

0.521

High

962980

RHG24
Rho GTPase-activating protein 24

2

1

High-throughput

0.521

High

963010

SH3G3
Endophilin-A3

2

3

High-throughput

0.521

High

963033

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.518

High

962955

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

2

High-throughput

0.515

High

962984

PDPR
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial

1

1

High-throughput

0.515

High

962991

TITIN
Titin

1

1

High-throughput

0.515

High

213883

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

362228

ABL1
Tyrosine-protein kinase ABL1

1

0

High-throughput

0.513

High

369037

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.513

High

663491

PRPH2
Peripherin-2

1

0

High-throughput

0.513

High

773848

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.513

High

904477

RENBP
N-acylglucosamine 2-epimerase

1

0

High-throughput

0.513

High

962934

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.513

High

962988

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.513

High

963002

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.513

High

962932

TLE1
Transducin-like enhancer protein 1

1

2

High-throughput

0.494

High

962953

RTP5
Receptor-transporting protein 5

1

0

High-throughput

0.493

High

962970

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

0

High-throughput

0.493

High

962939

STRN3
Striatin-3

1

4

High-throughput

0.489

High

962975

APTX
Aprataxin

1

2

High-throughput

0.489

High

962986

NOXO1
NADPH oxidase organizer 1

1

1

High-throughput

0.489

High

963009

ARI3A
AT-rich interactive domain-containing protein 3A

1

1

High-throughput

0.489

High

962941

STK3
Serine/threonine-protein kinase 3

1

1

High-throughput

0.481

High

872145

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.479

High

176046

KDM6B
Lysine-specific demethylase 6B

1

1

High-throughput

0.479

High

241278

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

281925

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.479

High

287266

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

339364

ETHE1
Persulfide dioxygenase ETHE1, mitochondrial

1

1

High-throughput

0.479

High

365353

PGK1
Phosphoglycerate kinase 1

1

1

High-throughput

0.479

High

389215

FINC
Fibronectin

1

1

High-throughput

0.479

High

400587

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

431050

LA
Lupus La protein

1

1

High-throughput

0.479

High

445804

ENOA
Alpha-enolase

1

5

High-throughput

0.479

High

476127

ANXA5
Annexin A5

1

2

High-throughput

0.479

High

566618

PDIA4
Protein disulfide-isomerase A4

1

6

High-throughput

0.479

High

571666

HCLS1
Hematopoietic lineage cell-specific protein

1

1

High-throughput

0.479

High

656089

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

4

High-throughput

0.479

High

697829

CALR
Calreticulin

1

1

High-throughput

0.479

High

715514

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

717428

PDIA3
Protein disulfide-isomerase A3

1

6

High-throughput

0.479

High

764604

CTNB1
Catenin beta-1

1

3

High-throughput

0.479

High

786052

LONM
Lon protease homolog, mitochondrial

1

3

High-throughput

0.479

High

882612

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

904531

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

921855

COPA
Coatomer subunit alpha

1

1

High-throughput

0.479

High

959109

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

961921

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

962921

SUMO2
Small ubiquitin-related modifier 2

1

2

High-throughput

0.479

High

962928

BASP1
Brain acid soluble protein 1

1

1

High-throughput

0.479

High

962929

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.479

High

962935

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

962937

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.479

High

962938

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

3

High-throughput

0.479

High

962947

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

962959

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

962960

SYAM
Alanine--tRNA ligase, mitochondrial

1

3

High-throughput

0.479

High

962974

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

1

High-throughput

0.479

High

962976

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.479

High

962982

ARL10
ADP-ribosylation factor-like protein 10

1

1

High-throughput

0.479

High

962995

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

962997

FXRD1
FAD-dependent oxidoreductase domain-containing protein 1

1

1

Small-scale

0.479

High

963005

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

963006

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

963007

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

963012

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

2

High-throughput

0.479

High

963019

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

963020

MTG2
Mitochondrial ribosome-associated GTPase 2

1

2

High-throughput

0.479

High

963027

PD1L1
Programmed cell death 1 ligand 1

1

1

High-throughput

0.479

High

963031

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

423893

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

0

Small-scale

0.460

High

61468

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

74013

MYO9A
Unconventional myosin-IXa

1

0

High-throughput

0.458

High

127920

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

High-throughput

0.458

High

138048

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

Small-scale

0.458

High

350828

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

375349

RASK
GTPase KRas

1

0

High-throughput

0.458

High

379985

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

395807

ESR1
Estrogen receptor

1

0

Small-scale

0.458

High

413526

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

439693

INSR
Insulin receptor

1

0

High-throughput

0.458

High

459528

PROF1
Profilin-1

1

0

High-throughput

0.458

High

470958

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

485028

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

519089

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

553158

KCRB
Creatine kinase B-type

1

0

High-throughput

0.458

High

565284

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

570871

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

599570

STMN1
Stathmin

1

0

High-throughput

0.458

High

615510

NELFE
Negative elongation factor E

1

0

High-throughput

0.458

High

623227

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

High-throughput

0.458

High

667703

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

685482

U2AF2
Splicing factor U2AF 65 kDa subunit

1

0

High-throughput

0.458

High

711621

3MG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.458

High

772125

MSX2
Homeobox protein MSX-2

1

0

High-throughput

0.458

High

822567

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

824072

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.458

High

827159

ARL1
ADP-ribosylation factor-like protein 1

1

0

High-throughput

0.458

High

840030

CASP3
Caspase-3

1

0

Small-scale

0.458

High

851860

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

866971

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

868996

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.458

High

926914

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

949127

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

957278

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

962923

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

962926

H31
Histone H3.1

1

0

High-throughput

0.458

High

962930

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

962933

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

962942

ILK
Scaffold protein ILK

1

0

High-throughput

0.458

High

962946

CUL3
Cullin-3

1

0

High-throughput

0.458

High

962948

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.458

High

962949

CKAP5
Cytoskeleton-associated protein 5

1

0

High-throughput

0.458

High

962950

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

962954

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

962957

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

962965

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

962966

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

0

High-throughput

0.458

High

962969

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

962977

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

962993

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

0

High-throughput

0.458

High

962996

MCUR1
Mitochondrial calcium uniporter regulator 1

1

0

High-throughput

0.458

High

962999

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

963011

TR61B
tRNA

1

0

High-throughput

0.458

High

963017

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

963018

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

963022

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

963023

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

963026

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

963028

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

963037

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

963039

YTHD2
YTH domain-containing family protein 2

1

0

High-throughput

0.458

High

64823

F186A
Protein FAM186A

1

1

High-throughput

0.437

High

405972

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

606537

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.437

High

830470

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

962964

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.437

High

962967

RHGBA
Rho GTPase-activating protein 11A

1

2

High-throughput

0.437

High

962971

RHG36
Rho GTPase-activating protein 36

1

2

High-throughput

0.437

High

962972

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

962973

SYDE1
Rho GTPase-activating protein SYDE1

1

3

High-throughput

0.437

High

962979

ARI3B
AT-rich interactive domain-containing protein 3B

1

1

High-throughput

0.437

High

962992

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.437

High

962994

TNR14
Tumor necrosis factor receptor superfamily member 14

1

1

High-throughput

0.437

High

963014

RHG39
Rho GTPase-activating protein 39

1

2

High-throughput

0.437

High

963029

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

1

High-throughput

0.437

High

963032

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

963035

NINL
Ninein-like protein

1

1

High-throughput

0.437

High

963038

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.437

High

529496

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

963000

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

963013

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

963024

GHC1
Mitochondrial glutamate carrier 1

1

0

High-throughput

0.426

High

962963

RIF1
Telomere-associated protein RIF1

1

1

High-throughput

0.417

High

327896

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

2

High-throughput

0.407

High

765314

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.407

High

952050

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

High-throughput

0.407

High

963016

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

2

High-throughput

0.407

High

962990

SELM
Selenoprotein M

2

0

High-throughput

0.316

High

963003

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

639593

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.282

High

736912

GBP2
Guanylate-binding protein 2

1

0

High-throughput

0.282

High

907302

APLP1
Amyloid beta precursor like protein 1

1

0

High-throughput

0.282

High

962943

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High

962951

DPYL1
Dihydropyrimidinase-related protein 1

1

0

High-throughput

0.282

High

963034

ZHX1
Zinc fingers and homeoboxes protein 1

1

0

High-throughput

0.282

High

962968

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.279

Low

963025

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

0

High-throughput

0.279

Low

70575

CQ051
Putative uncharacterized protein LINC02693

1

0

High-throughput

0.269

Low

176740

MCF2L
Guanine nucleotide exchange factor DBS

1

0

High-throughput

0.269

Low

962927

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

0

High-throughput

0.269

Low

962931

IRF8
Interferon regulatory factor 8

1

0

High-throughput

0.269

Low

962983

JMY
Junction-mediating and -regulatory protein

1

0

High-throughput

0.269

Low

963021

SYNCI
Syncoilin

1

0

High-throughput

0.269

Low

224962

TLX3
T-cell leukemia homeobox protein 3

1

0

High-throughput

0.261

Low

962952

NFAC4
Nuclear factor of activated T-cells, cytoplasmic 4

1

0

High-throughput

0.261

Low

962962

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

105690

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

239790

PCDH7
Protocadherin-7

1

0

High-throughput

0.249

Low

320844

ZN432
Zinc finger protein 432

1

0

High-throughput

0.249

Low

324706

HEXI1
Protein HEXIM1

1

0

High-throughput

0.249

Low

443040

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

High-throughput

0.249

Low

538931

EPB41
Protein 4.1

1

0

High-throughput

0.249

Low

583517

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

0

High-throughput

0.249

Low

635787

PTMS
Parathymosin

1

0

High-throughput

0.249

Low

651251

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.249

Low

962922

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

962940

REST
RE1-silencing transcription factor

1

0

High-throughput

0.249

Low

962944

OS9
Protein OS-9

1

0

High-throughput

0.249

Low

962945

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

962956

ITSN1
Intersectin-1

1

0

High-throughput

0.249

Low

962961

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.249

Low

962978

FBX11
F-box only protein 11

1

0

High-throughput

0.249

Low

962981

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

962987

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low

962998

OPTN
Optineurin

1

0

High-throughput

0.249

Low

963004

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

963030

TRM7
tRNA

1

0

High-throughput

0.249

Low

963036

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

116512

H7C1K6
Interferon induced protein 44 like

1

0

High-throughput

0.232

Low

963001

S41A3
Solute carrier family 41 member 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025