HitPredict

Interactor 1: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37059091
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 256 Hs			1 1834
+	Hs
		1096996 PRDX4_HUMAN (35-255): 3.39e-103: 302: 58.82		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		732355 PRDX2_HUMAN (58-255): 2.08e-104: 302: 63.13		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		1057208 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		854012 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		1030633 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		ANK2_HUMAN (790-1770): 6.65e-09: 63.5: 12.86