HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.748

The method score is based on:

Property Details
Experiments 27173435, 27684187, 29789528, 33643786, 23245941, 22234184, 21376238, 24976009
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 14 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 781
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024