Protein: RL12B
Large ribosomal subunit protein uL11B (60S ribosomal protein L12-B) (L15) (YL23)

Gene: RL12B, RPL12B
Organism: Saccharomyces cerevisiae S288C
Interactions: 228
UniProt ID: P0CX54

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005829 - cytosol
GO:0006412 - translation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

514323

LSG1
Large subunit GTPase 1

3

1

High-throughput

0.817

High

427094

RLA0
Large ribosomal subunit protein uL10

2

2

Small-scale

0.754

High

514285

NMD3
60S ribosomal export protein NMD3

3

1

Small-scale

0.640

High

514214

RL12B
Large ribosomal subunit protein uL11B

1

2

High-throughput

0.618

High

514257

MRT4
Ribosome assembly factor MRT4

1

2

Small-scale

0.618

High

514290

RBG1
Ribosome-interacting GTPase 1

1

1

High-throughput

0.618

High

514266

RPF2
Ribosome biogenesis protein RPF2

2

1

High-throughput

0.601

High

433381

RL26A
Large ribosomal subunit protein uL24A

2

1

High-throughput

0.584

High

514219

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.584

High

514241

RL16A
Large ribosomal subunit protein uL13A

2

1

High-throughput

0.584

High

514248

ZUO1
Zuotin

2

2

High-throughput

0.584

High

514268

GBLP
Small ribosomal subunit protein RACK1

2

4

Small-scale

0.584

High

514282

SSZ1
Ribosome-associated complex subunit SSZ1

2

1

High-throughput

0.584

High

514305

RL10
Large ribosomal subunit protein uL16

2

1

Small-scale

0.584

High

514308

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

514378

TMA46
Translation machinery-associated protein 46

2

1

High-throughput

0.584

High

514233

SIS1
Protein SIS1

2

0

High-throughput

0.576

High

514373

RLP24
Ribosome biogenesis protein RLP24

2

3

Small-scale

0.571

High

392087

HSP82
ATP-dependent molecular chaperone HSP82

2

0

High-throughput

0.559

High

409872

RL25
Large ribosomal subunit protein uL23

2

0

High-throughput

0.559

High

513608

RL2A
Large ribosomal subunit protein uL2A

2

0

High-throughput

0.559

High

514273

GID4
GID complex substrate-recognition subunit 4

2

0

High-throughput

0.559

High

514291

IF2P
Eukaryotic translation initiation factor 5B

2

0

High-throughput

0.559

High

514320

DXO
Decapping nuclease RAI1

2

0

Small-scale

0.559

High

514376

RS10A
Small ribosomal subunit protein eS10A

2

0

High-throughput

0.559

High

514293

NUG1
Nuclear GTP-binding protein NUG1

1

1

High-throughput

0.553

High

514330

PBP1
PAB1-binding protein 1

1

0

Small-scale

0.529

High

514387

RQC2
Ribosome quality control complex subunit 2

1

0

High-throughput

0.517

High

514246

XPO1
Exportin-1

1

1

High-throughput

0.489

High

154122

RL36B
Large ribosomal subunit protein eL36B

1

1

High-throughput

0.479

High

394145

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.479

High

409674

RL24A
Large ribosomal subunit protein eL24A

1

3

High-throughput

0.479

High

427528

RLA1
Large ribosomal subunit protein P1A

1

1

High-throughput

0.479

High

432457

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.479

High

432781

RL9A
Large ribosomal subunit protein uL6A

1

2

High-throughput

0.479

High

432960

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.479

High

433124

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.479

High

433952

RL33A
Large ribosomal subunit protein eL33A

1

1

High-throughput

0.479

High

434498

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.479

High

436289

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

4

High-throughput

0.479

High

502781

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

503341

RL11A
Large ribosomal subunit protein uL5A

1

2

High-throughput

0.479

High

503735

RL27A
Large ribosomal subunit protein eL27A

1

1

High-throughput

0.479

High

503882

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.479

High

509858

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

4

High-throughput

0.479

High

512194

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

513440

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.479

High

514220

RLA3
Large ribosomal subunit protein P1B

1

1

High-throughput

0.479

High

514221

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.479

High

514222

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.479

High

514224

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.479

High

514225

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

514227

RL8A
Large ribosomal subunit protein eL8A

1

1

High-throughput

0.479

High

514231

RL24B
Large ribosomal subunit protein eL24B

1

3

High-throughput

0.479

High

514234

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

514238

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

514239

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.479

High

514240

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.479

High

514242

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.479

High

514245

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.479

High

514247

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

3

High-throughput

0.479

High

514263

RL14A
Large ribosomal subunit protein eL14A

1

2

High-throughput

0.479

High

514271

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

1

High-throughput

0.479

High

514279

RL14B
Large ribosomal subunit protein eL14B

1

2

High-throughput

0.479

High

514299

RL34B
Large ribosomal subunit protein eL34B

1

1

High-throughput

0.479

High

514303

RLP7
Ribosome biogenesis protein RLP7

1

2

High-throughput

0.479

High

514304

RL33B
Large ribosomal subunit protein eL33B

1

1

High-throughput

0.479

High

514309

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.479

High

514314

RL37A
Large ribosomal subunit protein eL37A

1

1

High-throughput

0.479

High

514317

RL9B
Large ribosomal subunit protein uL6B

1

2

High-throughput

0.479

High

514318

RL37B
Large ribosomal subunit protein eL37B

1

1

High-throughput

0.479

High

514325

RL26B
Large ribosomal subunit protein uL24B

1

1

High-throughput

0.479

High

514334

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.479

High

514336

JJJ1
J protein JJJ1

1

2

High-throughput

0.479

High

514341

RL22B
Large ribosomal subunit protein eL22B

1

2

High-throughput

0.479

High

514342

RL34A
Large ribosomal subunit protein eL34A

1

1

High-throughput

0.479

High

514343

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.479

High

514345

PVH1
Tyrosine-protein phosphatase YVH1

1

1

Small-scale

0.479

High

514346

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.479

High

514348

RL21A
Large ribosomal subunit protein eL21A

1

1

High-throughput

0.479

High

514350

RLI1
Translation initiation factor RLI1

1

1

High-throughput

0.479

High

514353

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.479

High

514358

HMO1
High mobility group protein 1

1

2

High-throughput

0.479

High

514369

NOC4
Nucleolar complex protein 4

1

1

High-throughput

0.479

High

514382

MAK21
Ribosome biogenesis protein MAK21

1

1

High-throughput

0.479

High

514383

RL7B
Large ribosomal subunit protein uL30B

1

2

High-throughput

0.479

High

514388

RL21B
Large ribosomal subunit protein eL21B

1

1

High-throughput

0.479

High

514389

RL13A
Large ribosomal subunit protein eL13A

1

1

High-throughput

0.479

High

514391

RL11B
Large ribosomal subunit protein uL5B

1

2

High-throughput

0.479

High

149524

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

382800

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

383065

RLA4
Large ribosomal subunit protein P2B

1

0

High-throughput

0.458

High

383456

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

414978

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.458

High

434224

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

434304

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.458

High

434736

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

435707

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

441642

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

454807

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

481949

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.458

High

503978

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

511115

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.458

High

511357

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.458

High

511531

RL44B
Large ribosomal subunit protein eL42B

1

0

High-throughput

0.458

High

511720

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.458

High

511896

RS30A
Small ribosomal subunit protein eS30A

1

0

High-throughput

0.458

High

512753

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

513933

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.458

High

514215

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

514216

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.458

High

514217

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.458

High

514228

PSB4
Proteasome subunit beta type-4

1

0

Small-scale

0.458

High

514243

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

514255

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

514256

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

514259

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

514261

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

514269

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

514272

IMB2
Importin subunit beta-2

1

0

High-throughput

0.458

High

514276

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

514281

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.458

High

514286

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.458

High

514287

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

514289

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

514312

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

514319

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

0

High-throughput

0.458

High

514324

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.458

High

514328

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

514344

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

514361

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

514364

LTN1
E3 ubiquitin-protein ligase listerin

1

0

Small-scale

0.458

High

514370

ELP1
Elongator complex protein 1

1

0

High-throughput

0.458

High

514218

SSBP1
Single-stranded nucleic acid-binding protein

1

2

High-throughput

0.457

High

403317

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

2

Small-scale

0.445

High

514252

HBS1
Elongation factor 1 alpha-like protein

1

3

Small-scale

0.445

High

514297

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

364267

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.437

High

438585

SC160
Protein SCP160

1

3

High-throughput

0.437

High

514236

GID7
GID complex subunit 7

1

2

High-throughput

0.437

High

514251

CHD1
Chromo domain-containing protein 1

1

2

High-throughput

0.437

High

514258

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.437

High

514260

SPT7
SAGA complex subunit SPT7

1

1

High-throughput

0.437

High

514264

DBP7
ATP-dependent RNA helicase DBP7

1

3

High-throughput

0.437

High

514270

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

2

High-throughput

0.437

High

514278

ECM29
Proteasome component ECM29

1

1

High-throughput

0.437

High

514288

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.437

High

514306

ELP2
Elongator complex protein 2

1

3

High-throughput

0.437

High

514321

VID30
GID complex subunit 1

1

2

High-throughput

0.437

High

514335

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.437

High

514337

NOP15
Ribosome biogenesis protein 15

1

1

High-throughput

0.437

High

514339

FAP1
FKBP12-associated protein 1

1

1

High-throughput

0.437

High

514340

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.437

High

514351

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.437

High

514354

HAS1
ATP-dependent RNA helicase HAS1

1

2

High-throughput

0.437

High

514356

ARX1
Probable metalloprotease ARX1

1

2

High-throughput

0.437

High

514368

HRQ1
ATP-dependent helicase HRQ1

1

2

Small-scale

0.437

High

514381

YRA1
RNA annealing protein YRA1

1

2

High-throughput

0.437

High

514386

DBP10
ATP-dependent RNA helicase DBP10

1

2

High-throughput

0.437

High

514390

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.437

High

514380

NOP53
Ribosome biogenesis protein NOP53

1

0

Small-scale

0.426

High

514223

CAF20
Cap-associated protein CAF20

2

0

Small-scale

0.305

High

514274

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.305

High

514295

ARB1
ABC transporter ATP-binding protein ARB1

2

0

High-throughput

0.305

High

514302

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

514322

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

2

0

High-throughput

0.305

High

514331

SDA1
Protein SDA1

2

0

High-throughput

0.305

High

514329

RAGCD
GTP-binding protein GTR2

1

0

High-throughput

0.288

High

514352

RMT2
Protein arginine N-methyltransferase 2

1

0

High-throughput

0.251

Low

514384

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.251

Low

367216

ATP6
ATP synthase subunit a

1

0

Small-scale

0.249

Low

454375

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.249

Low

514226

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.249

Low

514229

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.249

Low

514230

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

514232

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.249

Low

514235

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.249

Low

514237

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

514244

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

514249

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

514250

ECM32
Putative ATP-dependent RNA helicase ECM32

1

0

High-throughput

0.249

Low

514253

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.249

Low

514254

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.249

Low

514262

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

514265

LAS1
Protein LAS1

1

0

Small-scale

0.249

Low

514267

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

514275

YB8A
Putative uncharacterized protein YBR285W

1

0

Small-scale

0.249

Low

514277

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.249

Low

514280

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

514284

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.249

Low

514292

NOC2
Nucleolar complex protein 2

1

0

Small-scale

0.249

Low

514294

BIM1
Protein BIM1

1

0

High-throughput

0.249

Low

514296

THO1
Protein THO1

1

0

High-throughput

0.249

Low

514298

TM108
Protein TMA108

1

0

High-throughput

0.249

Low

514300

ULP2
Ubiquitin-like-specific protease 2

1

0

Small-scale

0.249

Low

514301

SNL1
HSP70 co-chaperone SNL1

1

0

Small-scale

0.249

Low

514307

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

514310

ALB1
Ribosome biogenesis protein ALB1

1

0

High-throughput

0.249

Low

514311

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

514313

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

514315

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

514316

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.249

Low

514326

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

514327

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.249

Low

514332

H1
Histone H1

1

0

High-throughput

0.249

Low

514333

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

0

Small-scale

0.249

Low

514338

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

514347

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.249

Low

514349

ELP3
Elongator complex protein 3

1

0

High-throughput

0.249

Low

514355

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

0

High-throughput

0.249

Low

514357

FIN1
Filament protein FIN1

1

0

Small-scale

0.249

Low

514359

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.249

Low

514360

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

514362

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.249

Low

514363

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

514365

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.249

Low

514366

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.249

Low

514367

RQC1
Ribosome quality control complex subunit 1

1

0

Small-scale

0.249

Low

514371

TSR1
Ribosome biogenesis protein TSR1

1

0

High-throughput

0.249

Low

514372

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

514374

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

514375

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.249

Low

514377

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

514379

KAD6
Adenylate kinase isoenzyme 6 homolog FAP7

1

0

Small-scale

0.249

Low

514385

HRT3
F-box protein HRT3

1

0

High-throughput

0.249

Low

514392

SUS1
SAGA complex subunit SUS1

1

0

High-throughput

0.249

Low

514283

RPF1
Ribosome production factor 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025