HitPredict - High confidence protein-protein interactions

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: PSN1 (P49768)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: PSEN1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.732

Property	Details
Experiments	9852041, 10341227, 11193155, 17360711, 9738936, 16126725
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001708 - cell fate specification GO:0001764 - neuron migration GO:0005634 - nucleus GO:0005654 - nucleoplasm and 18 others more... GO:0005813 - centrosome GO:0005886 - plasma membrane GO:0005938 - cell cortex GO:0010628 - positive regulation of gene expression GO:0010629 - negative regulation of gene expression GO:0016020 - membrane GO:0030054 - cell junction GO:0032991 - protein-containing complex GO:0042734 - presynaptic membrane GO:0043065 - positive regulation of apoptotic process GO:0043066 - negative regulation of apoptotic process GO:0045296 - cadherin binding GO:0045893 - positive regulation of DNA-templated transcription GO:0048538 - thymus development GO:0050808 - synapse organization GO:0097190 - apoptotic signaling pathway GO:0098609 - cell-cell adhesion GO:0098978 - glutamatergic synapse
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	781
Hs

1	467

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Last updated: 15 Jul 2024