HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, 28877994
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0030054 - cell junction GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 781 Hs			1 1121
+	Hs
		542361 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		717352 CTNB1_HUMAN (1-781): 0: 626: 100.00		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		717450 CTNB1_HUMAN (1-781): 0: 626: 100.00		PKHA6_HUMAN (107-951): 1.85e-57: 218: 27.16
+	Hs
		717206 CTNB1_HUMAN (1-781): 0: 626: 100.00		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		717359 CTNB1_HUMAN (1-781): 0: 626: 100.00		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		716910 CTNB1_HUMAN (1-781): 0: 626: 100.00		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		125185 CTNB1_HUMAN (1-781): 0: 626: 100.00		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		131457 IMA4_HUMAN (220-681): 6.79e-68: 235: 15.25		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		717347 CTNB1_HUMAN (1-781): 0: 626: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		717289 CTNB1_HUMAN (1-781): 0: 626: 100.00		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Hs
		542383 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		542452 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		542246 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		542446 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		542467 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91
+	Ce
		86391 H2L2I2_CAEEL (89-738): 6.48e-98: 321: 31.20		C1P633_CAEEL (7-464): 1.13e-46: 184: 11.64
+	Ce
		86414 HMP2_CAEEL (89-738): 1.07e-96: 316: 31.20		C1P635_CAEEL (7-464): 1.64e-44: 177: 11.64
+	Hs
		124990 IMA4_HUMAN (220-681): 6.79e-68: 235: 15.25		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		238738 IMA7_HUMAN (200-683): 8.41e-73: 249: 16.97		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		131510 IMA4_HUMAN (220-681): 6.79e-68: 235: 15.25		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84