HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: PAR3L (Q8TEW8)
Partitioning defective 3 homolog B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein) (PAR3-beta) (Partitioning defective 3-like protein) (PAR3-L protein)
Gene: PARD3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005912 - adherens junction GO:0005923 - bicellular tight junction GO:0005938 - cell cortex GO:0007155 - cell adhesion GO:0030054 - cell junction and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 781 Hs			1 1205
+	Hs
		717226 CTNB1_HUMAN (1-781): 0: 626: 100.00		PARD3_HUMAN (1-1181): 5.16e-119: 403: 34.95
+	Hs
		542388 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		PARD3_HUMAN (1-1181): 5.16e-119: 403: 34.95
+	Mm
		970142 CTNB1_MOUSE (1-781): 0: 624: 99.87		DLG4_MOUSE (334-877): 1.2e-48: 187: 16.58
+	Hs
		717039 CTNB1_HUMAN (1-781): 0: 626: 100.00		DLG1_HUMAN (47-699): 1.29e-44: 177: 11.61
+	Hs
		717076 CTNB1_HUMAN (1-781): 0: 626: 100.00		SCRIB_HUMAN (363-1198): 3.45e-31: 135: 12.27
+	Hs
		717151 CTNB1_HUMAN (1-781): 0: 626: 100.00		MAGI3_HUMAN (132-1146): 1.53e-29: 130: 12.28
+	Mm
		250615 CTNB1_MOUSE (1-781): 0: 624: 99.87		LNX1_MOUSE (289-743): 1.22e-27: 122: 15.18
+	Hs
		717459 CTNB1_HUMAN (1-781): 0: 626: 100.00		GRIP1_HUMAN (166-1165): 7.06e-21: 101: 11.36
+	Rn
		957063 CTNB1_RAT (1-781): 0: 625: 99.74		GRIP1_RAT (166-1105): 1.27e-18: 94.2: 11.33
+	Mm
		970159 CTNB1_MOUSE (1-781): 0: 624: 99.87		GRIP1_MOUSE (31-615): 8.43e-16: 85.1: 12.26
+	Hs
		280027 CTNB1_HUMAN (1-781): 0: 626: 100.00		MPDZ_HUMAN (499-735): 8.56e-13: 75.4: 18.83
+	Hs
		717037 CTNB1_HUMAN (1-781): 0: 626: 100.00		PTN13_HUMAN (138-337): 1.02e-12: 75.4: 14.71
+	Hs
		717292 CTNB1_HUMAN (1-781): 0: 626: 100.00		MAGI1_HUMAN (333-687): 4.75e-12: 73.1: 13.58
+	Rn
		291512 CTNB1_RAT (1-781): 0: 625: 99.74		MAGI2_RAT (345-1124): 1.59e-11: 71.2: 10.33
+	Hs
		134936 IMA3_HUMAN (198-681): 7.05e-69: 237: 14.34		PARD3_HUMAN (1-1181): 5.16e-119: 403: 34.95
+	Dm
		578635 ARM_DROME (1-780): 9.15e-160: 486: 64.49		Q0KHR3_DROME (734-884): 3.06e-10: 67.2: 29.80
+	Hs
		119773 ARVC_HUMAN (202-771): 5.66e-94: 316: 18.66		LNX1_HUMAN (289-749): 3.58e-27: 121: 15.17
+	Ce
		86391 H2L2I2_CAEEL (89-738): 6.48e-98: 321: 31.20		C1P633_CAEEL (303-817): 1.37e-25: 116: 14.39
+	Ce
		86414 HMP2_CAEEL (89-738): 1.07e-96: 316: 31.20		C1P635_CAEEL (59-457): 4.14e-18: 92.7: 14.73
+	Ce
		88183 HMP2_CAEEL (89-738): 1.07e-96: 316: 31.20		D3YT29_CAEEL (127-289): 1.64e-11: 70.8: 12.27