Protein: KAD2
Adenylate kinase (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate kinase cytosolic and mitochondrial) (Adenylate monophosphate kinase)

Gene: KAD2, ADK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 72
UniProt ID: P07170

Gene Ontology (top 5):
GO:0003688 - DNA replication origin binding
GO:0004017 - AMP kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

450705

DBF2
Cell cycle protein kinase DBF2

2

3

Small-scale

0.602

High

450730

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

450724

ICP55
Intermediate cleaving peptidase 55

2

0

High-throughput

0.576

High

450700

PHO85
Cyclin-dependent protein kinase PHO85

1

2

High-throughput

0.536

High

450716

PLPHP
Pyridoxal phosphate homeostasis protein

1

1

High-throughput

0.536

High

450694

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.518

High

450741

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.513

High

450706

RAD53
Serine/threonine-protein kinase RAD53

1

4

High-throughput

0.501

High

450708

KC12
Casein kinase I homolog 2

1

3

High-throughput

0.501

High

450717

KSP1
Serine/threonine-protein kinase KSP1

1

5

High-throughput

0.501

High

450723

RSP5
E3 ubiquitin-protein ligase RSP5

1

2

High-throughput

0.501

High

450737

VID30
GID complex subunit 1

1

1

High-throughput

0.501

High

450742

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

5

High-throughput

0.501

High

450751

SKS1
Serine/threonine-protein kinase SKS1

1

3

High-throughput

0.501

High

450703

UBC1
Ubiquitin-conjugating enzyme E2 1

1

0

High-throughput

0.493

High

450691

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.480

High

450729

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

358933

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.479

High

367647

ENO1
Enolase 1

1

1

High-throughput

0.479

High

367851

ENO2
Enolase 2

1

1

High-throughput

0.479

High

392003

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.479

High

439185

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.479

High

450698

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

450713

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.479

High

450714

GBLP
Small ribosomal subunit protein RACK1

1

1

Small-scale

0.479

High

450715

ATG8
Autophagy-related protein 8

1

2

High-throughput

0.479

High

450702

MYO2
Myosin-2

1

0

Small-scale

0.460

High

450752

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.460

High

364869

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.458

High

365521

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

368380

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

368544

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.458

High

416339

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

450695

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

450696

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

450697

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.458

High

450704

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

450707

TKT1
Transketolase 1

1

0

High-throughput

0.458

High

450709

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

450712

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

450718

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

High-throughput

0.458

High

450719

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

450720

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

450722

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

450728

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.458

High

450733

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

450735

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

0

High-throughput

0.458

High

450738

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

450740

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.458

High

450744

COFI
Cofilin

1

0

High-throughput

0.458

High

450747

ZEO1
Protein ZEO1

1

0

High-throughput

0.458

High

450748

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

450699

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.457

High

450739

YG3A
Uncharacterized protein YGR130C

1

2

High-throughput

0.457

High

450692

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

450693

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

450725

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

450743

ULP1
Ubiquitin-like-specific protease 1

1

2

High-throughput

0.439

High

450710

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

450711

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.437

High

450749

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.437

High

450750

SMT3
Ubiquitin-like protein SMT3

1

1

High-throughput

0.437

High

450732

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

450721

TEM1
Protein TEM1

1

0

High-throughput

0.279

Low

450746

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.279

Low

450701

PDI
Protein disulfide-isomerase

1

0

High-throughput

0.249

Low

450726

APQ12
Nuclear membrane organization protein APQ12

1

0

High-throughput

0.249

Low

450727

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

450731

PTR3
SPS-sensor component PTR3

1

0

High-throughput

0.249

Low

450734

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

450736

CWH41
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.249

Low

450745

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025