HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: FERM2 (Q96AC1)
Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1)
Gene: FERMT2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

The method score is based on:

Property	Details
Experiments	27713156, 22699938
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 10 others more... GO:0005912 - adherens junction GO:0005925 - focal adhesion GO:0005938 - cell cortex GO:0007155 - cell adhesion GO:0007160 - cell-matrix adhesion GO:0010718 - positive regulation of epithelial to mesenchymal transition GO:0019901 - protein kinase binding GO:0030054 - cell junction GO:0045669 - positive regulation of osteoblast differentiation GO:0046332 - SMAD binding
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	781
Hs

1	680

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024