HitPredict

Interactor 1: DOCK2 (Q92608)
Dedicator of cytokinesis protein 2
Gene: DOCK2

Interactor 2: ELMO2 (Q96JJ3)
Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A)
Gene: ELMO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32203420
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DOCK_N~PH_12
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1830 Hs			1 720
+	Hs
		1267020 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Mm
		1207130 DOCK2_MOUSE (1-1830): 0: 2456: 95.08		ELMO1_MOUSE (1-718): 0: 1010: 75.34
+	Hs
		1050489 DOCK1_HUMAN (1-1783): 0: 2214: 59.96		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Mm
		1206593 DOCK1_MOUSE (1-1783): 0: 2199: 59.82		ELMO2_MOUSE (1-720): 0: 1042: 97.13
+	Hs
		1050484 DOCK1_HUMAN (1-1783): 0: 2214: 59.96		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Mm
		1207128 DOCK1_MOUSE (1-1783): 0: 2199: 59.82		ELMO1_MOUSE (1-718): 0: 1010: 75.34
+	Hs
		1295265 DOCK5_HUMAN (1-1750): 0: 2121: 55.64		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Hs
		1050487 DOCK1_HUMAN (1-1783): 0: 2214: 59.96		ELMO3_HUMAN (1-718): 0: 944: 50.49
+	Mm
		1207312 DOCK1_MOUSE (1-1783): 0: 2199: 59.82		ELMO3_MOUSE (1-719): 0: 944: 51.11
+	Hs
		1267024 DOCK5_HUMAN (1-1750): 0: 2121: 55.64		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Hs
		1285559 DOCK5_HUMAN (1-1750): 0: 2121: 55.64		ELMO3_HUMAN (1-718): 0: 944: 50.49
+	Hs
		1224227 DOCK3_HUMAN (4-1657): 0: 1911: 37.48		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Hs
		1224220 DOCK3_HUMAN (4-1657): 0: 1911: 37.48		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Hs
		1230992 DOCK4_HUMAN (4-1613): 0: 1841: 38.62		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Hs
		1061751 Q149N5_HUMAN (4-1613): 0: 1815: 37.43		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Hs
		1224225 DOCK3_HUMAN (4-1657): 0: 1911: 37.48		ELMO3_HUMAN (1-718): 0: 944: 50.49
+	Hs
		1230987 DOCK4_HUMAN (4-1613): 0: 1841: 38.62		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Dm
		1362934 Q9VCH4_DROME (1-1762): 0: 1995: 38.85		Q9VKB2_DROME (5-718): 0: 839: 44.60
+	Hs
		1230990 DOCK4_HUMAN (4-1613): 0: 1841: 38.62		ELMO3_HUMAN (1-718): 0: 944: 50.49
+	Dm
		81396 B7Z0R2_DROME (4-1690): 0: 1802: 36.61		Q9VKB2_DROME (5-718): 0: 839: 44.60