HitPredict

Interactor 1: PDIA3 (P30101)
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)
Gene: PDIA3

Interactor 2: HSP13 (P48723)
Heat shock 70 kDa protein 13 (Heat shock protein family A member 13) (Microsomal stress-70 protein ATPase core) (Stress-70 protein chaperone microsome-associated 60 kDa protein)
Gene: HSPA13

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005783 - endoplasmic reticulum GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 471
+	Hs
		536575 PDIA3_HUMAN (1-505): 4.08e-163: 473: 100.00		HSP7C_HUMAN (28-469): 0: 584: 36.91
+	Hs
		452195 PDIA1_HUMAN (3-482): 3.49e-117: 356: 33.06		HSP13_HUMAN (1-471): 0: 602: 100.00
+	Hs
		452139 PDIA1_HUMAN (3-482): 3.49e-117: 356: 33.06		HSP7C_HUMAN (28-469): 0: 584: 36.91
+	Sc
		522988 PDI_YEAST (13-483): 2.91e-87: 279: 27.55		HSP71_YEAST (31-469): 0: 566: 36.34
+	Hs
		566589 PDIA4_HUMAN (376-494): 1.94e-23: 106: 34.71		HSP13_HUMAN (1-471): 0: 602: 100.00
+	Hs
		536405 PDIA4_HUMAN (376-494): 1.94e-23: 106: 34.71		HSP7C_HUMAN (28-469): 0: 584: 36.91
+	Hs
		876682 PDIA6_HUMAN (385-471): 3.14e-10: 64.3: 40.91		HSP13_HUMAN (1-471): 0: 602: 100.00
+	Sc
		481470 PDI_YEAST (13-483): 2.91e-87: 279: 27.55		HSP73_YEAST (32-449): 3.07e-86: 279: 39.48