Interactor 1: IL13 (P35225)
Interleukin-13 (IL-13)
Gene: IL13

Interactor 2: I13R2 (Q14627)
Interleukin-13 receptor subunit alpha-2 (IL-13 receptor subunit alpha-2) (IL-13R subunit alpha-2) (IL-13R-alpha-2) (IL-13RA2) (Interleukin-13-binding protein) (CD antigen CD213a2)
Gene: IL13RA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.955

The method score is based on:

Property Details
Experiments 22952195, 11313257, 8663118, 20223216, 27629921, 23972995
Identification Methods pull down, biochemical, x-ray crystallography, isothermal titration calorimetry, molecular sieving, surface plasmon resonance, protein cross-linking with a bifunctional reagent, saturation binding, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL13~IL6Ra-bind
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0009897 - external side of plasma membrane
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 146
Hs

1 380
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024