HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: ENL (Q03111)
Protein ENL (YEATS domain-containing protein 1)
Gene: MLLT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	25921070
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 559
+	Hs
		717754 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		718068 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		CBP_HUMAN (36-507): 4.66e-27: 118: 11.67
+	Hs
		974513 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		ENL_HUMAN (1-559): 7.97e-77: 255: 100.00
+	Hs
		788062 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		AF9_HUMAN (1-559): 6.95e-74: 247: 52.36
+	Hs
		974511 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		ENL_HUMAN (1-559): 7.97e-77: 255: 100.00
+	Mm
		57329 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		AF9_MOUSE (1-559): 3.55e-75: 250: 52.36
+	Hs
		788060 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		AF9_HUMAN (1-559): 6.95e-74: 247: 52.36
+	Mm
		1208638 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		Q8CJ76_MOUSE (1-559): 2.74e-71: 240: 84.08
+	Mm
		1321740 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		Q9ERL0_MOUSE (1-559): 3.47e-70: 236: 84.44
+	Hs
		1108526 PCGF3_HUMAN (4-228): 4.43e-72: 225: 34.03		CBP_HUMAN (36-507): 4.66e-27: 118: 11.67
+	Hs
		584938 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		987957 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		282445 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		YETS4_HUMAN (6-138): 1.04e-41: 151: 25.18