Protein: 2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit (PR65) (Protein phosphatase PP2A regulatory subunit A)

Gene: 2AAA, Pp2A-29B
Organism: Drosophila melanogaster
Interactions: 187
UniProt ID: P36179

Gene Ontology (top 5):
GO:0000159 - protein phosphatase type 2A complex
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

782764

Q9VB23
Serine/threonine protein phosphatase 2A regulatory subunit

5

20

High-throughput

0.912

High

782770

Q9VEC6
LD29902p

2

20

Small-scale

0.754

High

661918

PP2A
Serine/threonine-protein phosphatase PP2A

2

20

High-throughput

0.737

High

782748

XPO1
Exportin-1

2

6

High-throughput

0.737

High

782776

IPO9
Importin-9

2

7

High-throughput

0.737

High

782798

Q9VN44
FI07923p

2

6

High-throughput

0.737

High

782707

SGO1
Shugoshin

4

0

Small-scale

0.651

High

92275

D3DML3
Connector of kinase to AP-1, isoform E

3

19

Small-scale

0.642

High

782807

Q9VSD6
D-Importin 7/RanBP7

1

6

High-throughput

0.575

High

704331

SYEP
Bifunctional glutamate/proline--tRNA ligase

2

1

High-throughput

0.571

High

782723

Q7KMQ0
26S proteasome regulatory subunit 7

2

5

High-throughput

0.571

High

782757

Q9V455
Importin subunit alpha

2

3

High-throughput

0.571

High

782779

Q9VHL2
T-complex protein 1 subunit eta

2

1

High-throughput

0.571

High

782802

Q9VQL1
serine--tRNA ligase

2

2

High-throughput

0.571

High

782817

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

2

2

High-throughput

0.571

High

782823

Q9VXQ5
Chaperonin containing TCP1 subunit 6

2

1

High-throughput

0.571

High

782689

2ABA
Protein phosphatase PP2A 55 kDa regulatory subunit

2

10

High-throughput

0.552

High

437976

PYR1
Multifunctional protein r

2

0

High-throughput

0.547

High

782741

Q8T8W3
AT21416p

2

0

High-throughput

0.547

High

782759

Q9V9Q4
LD43819p

2

0

High-throughput

0.547

High

782762

Q9VAW3
glutamine--fructose-6-phosphate transaminase

2

0

High-throughput

0.547

High

782791

NFS1
Cysteine desulfurase, mitochondrial

2

0

High-throughput

0.547

High

782806

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

2

0

High-throughput

0.547

High

782828

Q9VZL3
very-long-chain enoyl-CoA reductase

2

0

High-throughput

0.547

High

782777

Q9VGY3
GEO12082p1

2

1

High-throughput

0.543

High

652007

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

2

2

High-throughput

0.521

High

715074

CLH
Clathrin heavy chain

2

1

High-throughput

0.521

High

782696

TCPG
T-complex protein 1 subunit gamma

2

2

High-throughput

0.521

High

782708

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

2

1

High-throughput

0.521

High

782721

Q7K3J0
T-complex protein 1 subunit theta

2

1

High-throughput

0.521

High

782733

Q8STG9
DSec61alpha

2

1

High-throughput

0.521

High

782745

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

2

3

High-throughput

0.521

High

782758

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

2

3

High-throughput

0.521

High

782761

Q9VAL7
Calnexin 99A, isoform A

2

1

High-throughput

0.521

High

782765

Q9VBU5
3-dehydrosphinganine reductase

2

2

High-throughput

0.521

High

782773

ATD3A
ATPase family AAA domain-containing protein 3A homolog

2

10

High-throughput

0.521

High

782803

Q9VQL7
Fatty acid synthase

2

1

High-throughput

0.521

High

782816

Q9VV75
AT02348p

2

1

High-throughput

0.521

High

782818

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

2

1

High-throughput

0.521

High

782820

Q9VWL0
Mec2

2

6

High-throughput

0.521

High

304837

E2F2
Transcription factor E2F2

1

2

High-throughput

0.508

High

782698

UBCD4
Ubiquitin-conjugating enzyme E2-22 kDa

1

1

High-throughput

0.508

High

782736

CSN3
COP9 signalosome complex subunit 3

1

3

High-throughput

0.508

High

782749

Q9U6R9
Gamma-soluble NSF attachment protein

1

2

High-throughput

0.508

High

782705

Q0KHR3
Bazooka, isoform B

1

3

Small-scale

0.504

High

782774

Q9VFR4
GH09754p

1

0

High-throughput

0.486

High

782750

JIL1
Chromosomal serine/threonine-protein kinase JIL-1

1

4

High-throughput

0.484

High

118242

M9NCY1
Lim3, isoform E

1

1

High-throughput

0.481

High

120029

M9PC68
Dpt-YFP repressor by overexpression, isoform D

1

1

High-throughput

0.481

High

782690

RAC1
Ras-related protein Rac1

1

6

High-throughput

0.481

High

304935

CRY1
Cryptochrome-1

1

4

High-throughput

0.479

High

782718

MOB4
MOB kinase activator-like 4

1

6

Small-scale

0.479

High

782720

Q7K3H0
LD28067p

1

3

High-throughput

0.479

High

782729

AKT1
RAC serine/threonine-protein kinase

1

2

High-throughput

0.479

High

782739

HIPPO
Serine/threonine-protein kinase hippo

1

19

Small-scale

0.479

High

782744

CYCG
Cyclin G

1

1

Small-scale

0.479

High

782832

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

6

High-throughput

0.479

High

782837

INT6
Integrator complex subunit 6

1

2

Small-scale

0.479

High

782839

IRS1
Insulin receptor substrate 1

1

2

High-throughput

0.479

High

68897

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

0

High-throughput

0.458

High

782738

TANT
Protein tantalus

1

0

High-throughput

0.458

High

782766

CRERF
Protein CREBRF homolog

1

0

Small-scale

0.458

High

782767

Q9VCQ7
LD40758p

1

0

Small-scale

0.458

High

782778

DALMA
Protein dalmatian

1

0

Small-scale

0.458

High

782780

Q9VHP9
Centromeric protein-C, isoform A

1

0

Small-scale

0.458

High

782800

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

0

High-throughput

0.458

High

782785

Q9VJ00
FI01025p

1

2

High-throughput

0.457

High

782796

Q9VLT9
Connector of kinase to AP-1, isoform A

1

20

High-throughput

0.457

High

782712

Q4QPZ6
IP05921p

1

1

High-throughput

0.451

High

55762

A1Z9K0
Uncharacterized protein, isoform B

1

2

High-throughput

0.445

High

58074

A1ZBE9
Methionine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.445

High

198027

PRS8
26S proteasome regulatory subunit 8

1

4

High-throughput

0.445

High

356724

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

4

High-throughput

0.445

High

451735

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

1

3

High-throughput

0.445

High

473545

RAP1
Ras-related protein Rap1

1

7

High-throughput

0.445

High

564953

ATNA
Sodium/potassium-transporting ATPase subunit alpha

1

2

High-throughput

0.445

High

613921

SGG
Protein kinase shaggy

1

4

High-throughput

0.445

High

669681

PSMD3
Probable 26S proteasome non-ATPase regulatory subunit 3

1

2

High-throughput

0.445

High

782691

ARF4
ADP ribosylation factor 4

1

2

High-throughput

0.445

High

782695

PRS4
26S proteasome regulatory subunit 4

1

5

High-throughput

0.445

High

782700

ARL2
ADP-ribosylation factor-like protein 2

1

3

High-throughput

0.445

High

782703

Q0E931
GTP-binding protein 1

1

4

High-throughput

0.445

High

782709

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

4

High-throughput

0.445

High

782710

MCM4
DNA replication licensing factor MCM4

1

3

High-throughput

0.445

High

782713

SARM1
NAD(+) hydrolase sarm1

1

3

High-throughput

0.445

High

782724

Q7KN75
Dodeca-satellite-binding protein 1, isoform A

1

1

High-throughput

0.445

High

782730

Q8IQZ7
FI19014p1

1

1

High-throughput

0.445

High

782731

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

782742

LDH
L-lactate dehydrogenase

1

1

High-throughput

0.445

High

782751

Q9V3V6
26S proteasome regulatory complex subunit p50

1

10

High-throughput

0.445

High

782752

Q9V3Z4
GH11341p

1

1

High-throughput

0.445

High

782753

Q9V405
26S proteasome regulatory subunit 6B

1

3

High-throughput

0.445

High

782781

ARL8
ADP-ribosylation factor-like protein 8

1

2

High-throughput

0.445

High

782783

Q9VI53
LD44267p

1

12

High-throughput

0.445

High

782784

DDX47
ATP-dependent RNA helicase DDX47

1

4

High-throughput

0.445

High

782790

Q9VK69
T-complex protein 1 subunit delta

1

3

High-throughput

0.445

High

782793

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.445

High

782794

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

1

High-throughput

0.445

High

782795

Q9VLS7
LD21067p

1

1

High-throughput

0.445

High

782814

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

High-throughput

0.445

High

782819

Q9VWI2
N(Alpha)-acetyltransferase 15/16, isoform A

1

3

High-throughput

0.445

High

782826

RENT1
Regulator of nonsense transcripts 1 homolog

1

2

High-throughput

0.445

High

782827

Q9VZ88
AT07585p

1

7

High-throughput

0.445

High

782830

Q9W0E4
Aminopeptidase

1

1

High-throughput

0.445

High

782834

Q9W215
GEO03726p1

1

2

High-throughput

0.445

High

782836

Q9W414
Regulatory particle triple-A ATPase 4

1

4

High-throughput

0.445

High

782841

SYQ
Probable glutamine--tRNA ligase

1

1

High-throughput

0.445

High

782810

Q9VTG5
AarF domain containing kinase 5, isoform A

1

2

High-throughput

0.439

High

782821

Q9VWT5
X-ray repair cross complementing 2

1

1

High-throughput

0.439

High

52642

A1Z729
NADP-retinol dehydrogenase

1

4

High-throughput

0.437

High

119566

M9PAY7
Pi3K21B, isoform C

1

3

High-throughput

0.437

High

120101

M9PCD4
Liprin-alpha, isoform E

1

8

Small-scale

0.437

High

782699

CCD1P
Probable cytochrome P450 12d1 proximal, mitochondrial

1

1

High-throughput

0.437

High

782716

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.437

High

782728

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

2

High-throughput

0.437

High

782763

Q9VAY2
Heat shock protein 83

1

4

High-throughput

0.437

High

782842

Q9Y162
vesicle-fusing ATPase

1

6

High-throughput

0.437

High

2702

A0A0B4LFU9
Anastral spindle 2, isoform B

1

0

High-throughput

0.426

High

51895

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.426

High

782692

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.426

High

782697

PFKA
ATP-dependent 6-phosphofructokinase

1

0

High-throughput

0.426

High

782701

ROP
Protein ROP

1

0

High-throughput

0.426

High

782706

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.426

High

782732

Q8MT58
Carnosine dipeptidase 2, isoform A

1

0

High-throughput

0.426

High

782735

Q8SY53
GH11935p

1

0

High-throughput

0.426

High

782743

FAXC
Failed axon connections

1

0

High-throughput

0.426

High

782754

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.426

High

782755

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

782772

Q9VEP0
Regulatory protein zeste

1

0

High-throughput

0.426

High

782775

ELP6
Elongator complex protein 6

1

0

High-throughput

0.426

High

782801

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.426

High

782812

FRL
Formin-like protein

1

0

High-throughput

0.426

High

782813

PYRG
CTP synthase

1

0

High-throughput

0.426

High

782822

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

782831

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

782811

Q9VTH5
Dpt-YFP repressor by overexpression, isoform B

1

1

High-throughput

0.417

High

55412

A1Z9E3
Elongation factor Tu

1

2

High-throughput

0.407

High

263362

PENG
Protein penguin

1

1

High-throughput

0.407

High

304110

RAB7
Ras-related protein Rab7

1

6

High-throughput

0.407

High

355917

O96692
small monomeric GTPase

1

7

High-throughput

0.407

High

782694

ACTZ
Actin-related protein 1

1

2

High-throughput

0.407

High

782704

Q0E9E2
Pyruvate carboxylase

1

1

High-throughput

0.407

High

782711

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

1

High-throughput

0.407

High

782714

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.407

High

782717

Q7JXU4
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.407

High

782727

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

1

High-throughput

0.407

High

782734

Q8SY39
ATP-dependent RNA helicase DDX54

1

5

High-throughput

0.407

High

782737

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.407

High

782740

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

3

High-throughput

0.407

High

782746

Q95WY3
Nucleolar protein 56

1

3

High-throughput

0.407

High

782747

Q960C7
NADP-retinol dehydrogenase

1

4

High-throughput

0.407

High

782760

Q9VAH7
N-terminal kinase-like protein

1

10

High-throughput

0.407

High

782768

DDX18
Probable ATP-dependent RNA helicase pitchoune

1

4

High-throughput

0.407

High

782771

Q9VEH0
Aluminum tubes, isoform A

1

4

High-throughput

0.407

High

782787

Q9VK06
Phospholipid-transporting ATPase

1

1

High-throughput

0.407

High

782789

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

2

High-throughput

0.407

High

782792

Q9VKU1
long-chain-fatty-acid--CoA ligase

1

9

High-throughput

0.407

High

782808

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.407

High

782824

Q9VXR5
ATP-binding cassette sub-family F member 2

1

2

High-throughput

0.407

High

782833

Q9W1H8
acetyl-CoA C-acyltransferase

1

1

High-throughput

0.407

High

782693

COPB
Coatomer subunit beta

2

0

High-throughput

0.298

High

782702

Q0E8E8
Phosphate carrier protein, mitochondrial

2

0

High-throughput

0.298

High

782715

Q6NP72
GEO09659p1

2

0

High-throughput

0.298

High

782719

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.298

High

782725

Q7KN94
Electron transfer flavoprotein subunit alpha

2

0

High-throughput

0.298

High

782756

KRH2
Krueppel homolog 2

2

0

High-throughput

0.298

High

782786

Q9VJD1
Glucosidase 2 subunit beta

2

0

High-throughput

0.298

High

782835

Q9W3N1
RH59310p

2

0

High-throughput

0.298

High

782782

Q9VHW0
AT07710p

1

0

High-throughput

0.265

Low

782809

Q9VSY9
Nuclear transcription factor Y subunit

1

0

High-throughput

0.265

Low

782722

Q7KLX3
Translocon-associated protein subunit delta

1

0

High-throughput

0.249

Low

782799

Q9VPR1
GH02075p

1

0

High-throughput

0.249

Low

782804

Q9VQS4
Spindly

1

0

High-throughput

0.249

Low

53109

A1Z7K8
AaRS-interacting multifunctional protein 1

1

0

High-throughput

0.232

Low

53670

A1Z843
Nodal modulator 3

1

0

High-throughput

0.232

Low

304185

ERD2
ER lumen protein-retaining receptor

1

0

High-throughput

0.232

Low

360517

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.232

Low

782726

DYM
Dymeclin

1

0

High-throughput

0.232

Low

782769

Q9VDK7
Signal recognition particle subunit SRP72

1

0

High-throughput

0.232

Low

782788

Q9VK46
Protein YIPF

1

0

High-throughput

0.232

Low

782797

Q9VM57
Septin interacting protein 2, isoform A

1

0

High-throughput

0.232

Low

782805

Q9VS47
Lysosomal dipeptide transporter MFSD1

1

0

High-throughput

0.232

Low

782815

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

0

High-throughput

0.232

Low

782825

Q9VXV6
Secretory carrier-associated membrane protein

1

0

High-throughput

0.232

Low

782829

Q9VZU8
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.232

Low

782838

Q9W4N8
LD30122p

1

0

High-throughput

0.232

Low

782840

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025