HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: CEP85 (Q6P2H3)
Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21)
Gene: CEP85

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34316702
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 326 Hs			1 762
+	Hs
		717915 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		CE85L_HUMAN (33-762): 5.08e-44: 172: 33.38
+	Hs
		717762 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		KIF5A_HUMAN (259-749): 5.37e-25: 113: 15.35
+	Hs
		717846 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		EEA1_HUMAN (92-676): 3.33e-18: 91.8: 10.59
+	Hs
		254450 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		ROCK2_HUMAN (316-734): 9.46e-15: 80.9: 11.64
+	Hs
		717921 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		CROCC_HUMAN (115-655): 1.33e-14: 80.2: 10.54
+	Hs
		717891 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		GRDN_HUMAN (340-687): 7.66e-13: 74.6: 20.46
+	Hs
		718062 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MY18A_HUMAN (330-673): 4.69e-09: 62.3: 17.90
+	Hs
		282679 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		CEP85_HUMAN (1-762): 9.11e-72: 251: 100.00
+	Hs
		1067462 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		EEA1_HUMAN (92-676): 3.33e-18: 91.8: 10.59
+	Hs
		584960 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		DCTN1_HUMAN (504-754): 1.94e-12: 73.2: 13.78
+	Hs
		1019301 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		DCTN1_HUMAN (504-754): 1.94e-12: 73.2: 13.78
+	Hs
		585020 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		RBCC1_HUMAN (407-745): 9.61e-09: 61.1: 19.78
+	Hs
		528393 TRIM6_HUMAN (5-189): 2.83e-49: 173: 16.67		MYH6_HUMAN (115-496): 3.81e-10: 66: 7.21
+	Hs
		522639 TRIM6_HUMAN (5-189): 2.83e-49: 173: 16.67		MYH7_HUMAN (110-485): 8.25e-10: 64.8: 7.32
+	Hs
		1078906 TRIM5_HUMAN (9-190): 3.01e-48: 170: 14.89		ITSN1_HUMAN (516-760): 2.94e-09: 63: 12.50
+	Hs
		1255682 TRIM5_HUMAN (9-190): 3.01e-48: 170: 14.89		RBCC1_HUMAN (407-745): 9.61e-09: 61.1: 19.78
+	Hs
		149258 TRIM4_HUMAN (10-198): 5.23e-47: 167: 17.05		CTRO_HUMAN (260-622): 2.7e-09: 63.1: 14.80
+	Hs
		1255683 TRIM4_HUMAN (10-198): 5.23e-47: 167: 17.05		RBCC1_HUMAN (407-745): 9.61e-09: 61.1: 19.78
+	Hs
		148711 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		CTRO_HUMAN (260-622): 2.7e-09: 63.1: 14.80
+	Hs
		282514 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		DESP_HUMAN (383-734): 5.95e-10: 65.3: 17.34