HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: ATX2 (Q99700)
Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein)
Gene: ATXN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	24457600, 34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 1313
+	Hs
		554277 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MUC1_HUMAN (699-1312): 1.2e-29: 130: 10.26
+	Hs
		718048 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		ATX2L_HUMAN (521-1304): 2.92e-19: 96.4: 18.02
+	Hs
		718128 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MINT_HUMAN (431-1274): 9.87e-12: 72.1: 8.75
+	Hs
		717688 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MAP1A_HUMAN (9-724): 9.52e-09: 62.5: 10.20
+	Hs
		1300927 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47
+	Hs
		585039 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47
+	Hs
		1223389 TRI22_HUMAN (1-198): 2.92e-50: 175: 14.56		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47
+	Hs
		1300908 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47
+	Hs
		988011 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47
+	Hs
		987995 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		KMT2C_HUMAN (54-860): 6.28e-10: 66.3: 9.19