HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	34316702
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 7388
+	Hs
		717606 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		717848 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		513833 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		DMD_HUMAN (239-1700): 1.65e-14: 84.4: 8.22
+	Hs
		718032 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SYNE1_HUMAN (343-1742): 3.05e-13: 80.2: 8.97
+	Hs
		717728 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Hs
		164573 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN2_HUMAN (3436-4815): 1.06e-11: 74.8: 9.59
+	Hs
		717709 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80
+	Hs
		717542 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		UTRN_HUMAN (428-1437): 8.81e-11: 71.9: 13.98
+	Hs
		521481 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Hs
		717799 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39
+	Hs
		718187 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN4_HUMAN (4289-5023): 8.23e-09: 65.5: 19.24
+	Hs
		584968 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		521464 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Hs
		1244129 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		SYNE1_HUMAN (343-1742): 3.05e-13: 80.2: 8.97
+	Hs
		282514 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		282627 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80
+	Hs
		282506 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Hs
		282645 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39
+	Hs
		963368 DTX3_HUMAN (17-62): 3.98e-10: 62.2: 39.13		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80