HitPredict

Interactor 1: PCGF2 (P35227)
Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144)
Gene: PCGF2

Interactor 2: NANOG (Q9H9S0)
Homeobox protein NANOG (Homeobox transcription factor Nanog) (hNanog)
Gene: NANOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26687479
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 305
+	Hs
		718207 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Hs
		595583 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		HXA5_HUMAN (2-165): 8.34e-36: 131: 20.69
+	Hs
		201868 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		HXA3_HUMAN (41-216): 2e-33: 128: 24.86
+	Hs
		1311543 PCGF1_HUMAN (2-232): 1.01e-61: 199: 35.42		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Hs
		1304113 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Hs
		585071 RO52_HUMAN (8-210): 4.32e-32: 127: 15.02		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Mm
		1194679 PCGF6_MOUSE (2-227): 6.81e-55: 184: 35.04		NANOG_MOUSE (1-303): 7.62e-40: 143: 54.98
+	Hs
		641545 PCGF1_HUMAN (2-232): 1.01e-61: 199: 35.42		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679164 PCGF1_HUMAN (2-232): 1.01e-61: 199: 35.42		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		641552 PCGF6_HUMAN (2-227): 3.54e-58: 193: 35.47		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		211952 PCGF1_HUMAN (2-232): 1.01e-61: 199: 35.42		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86
+	Mm
		1194680 RING2_MOUSE (4-234): 2.19e-45: 159: 17.49		NANOG_MOUSE (1-303): 7.62e-40: 143: 54.98
+	Hs
		641464 PCGF5_HUMAN (1-221): 5.43e-53: 177: 31.88		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679129 PCGF5_HUMAN (1-221): 5.43e-53: 177: 31.88		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		213349 PCGF5_HUMAN (1-221): 5.43e-53: 177: 31.88		TLX2_HUMAN (76-157): 1.26e-27: 110: 37.35
+	Hs
		211899 PCGF5_HUMAN (1-221): 5.43e-53: 177: 31.88		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86
+	Hs
		641538 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679160 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		641384 RING1_HUMAN (3-127): 4.75e-28: 114: 23.26		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		211843 RING1_HUMAN (3-127): 4.75e-28: 114: 23.26		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86