HitPredict

Interactor 1: RADI (P35241)
Radixin
Gene: RDX

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane GO:0010628 - positive regulation of gene expression GO:0030335 - positive regulation of cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 583 Hs			1 839
+	Hs
		719502 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		384207 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		384378 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		609192 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73
+	Hs
		507828 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		507885 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		507865 MOES_HUMAN (1-583): 2.8e-161: 474: 80.96		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		546928 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		607901 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		507884 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		607883 MOES_HUMAN (1-583): 2.8e-161: 474: 80.96		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		607900 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		384164 EPB41_HUMAN (3-553): 1.19e-125: 392: 20.48		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		434145 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		434144 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		547024 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		DDR1_HUMAN (535-824): 9.4e-68: 244: 43.63
+	Hs
		719701 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		435541 MOES_HUMAN (1-583): 2.8e-161: 474: 80.96		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		719462 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		DDR1_HUMAN (535-824): 9.4e-68: 244: 43.63
+	Hs
		435559 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16