HitPredict

Interactor 1: RFA3 (P35244)
Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)
Gene: RPA3

Interactor 2: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.724

Property	Details
Experiments	30279242, 12724401, 24126761, 37827155, 24332808, 15775963
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000723 - telomere maintenance GO:0000724 - double-strand break repair via homologous recombination GO:0003697 - single-stranded DNA binding GO:0005654 - nucleoplasm GO:0006260 - DNA replication and 1 others more... GO:0006281 - DNA repair
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 121 Hs			1 1417
+	Hs
		295501 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		RECQ5_HUMAN (646-1075): 4.96e-148: 478: 39.15
+	Hs
		720443 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		WRN_HUMAN (487-1294): 3.74e-143: 475: 23.02
+	Hs
		133900 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		DDX3X_HUMAN (488-1052): 1.62e-133: 428: 14.86
+	Hs
		719904 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		RECQ1_HUMAN (626-1233): 2.63e-131: 422: 34.75
+	Hs
		571332 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		DDX5_HUMAN (549-1025): 7.25e-126: 406: 19.03
+	Hs
		721068 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		DDX17_HUMAN (581-1104): 6.52e-122: 399: 17.93
+	Hs
		721403 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		DDX47_HUMAN (672-1004): 4.35e-11: 68.9: 26.36