HitPredict

Interactor 1: RFA3 (P35244)
Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)
Gene: RPA3

Interactor 2: TRIPC (Q14669)
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)
Gene: TRIP12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37827155, 24332808
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006281 - DNA repair
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 121 Hs			1 1992
+	Hs
		721167 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		ITCH_HUMAN (1018-1990): 0: 591: 17.29
+	Hs
		721199 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		NED4L_HUMAN (989-1990): 0: 588: 16.37
+	Hs
		720630 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		HERC4_HUMAN (1290-1991): 1.24e-156: 513: 18.47
+	Hs
		131387 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73
+	Hs
		134839 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		IMA3_HUMAN (365-866): 1.41e-154: 488: 13.33
+	Hs
		720285 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		UBE3A_HUMAN (1492-1991): 2.41e-140: 462: 27.02
+	Hs
		721763 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52
+	Hs
		720808 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72