HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 97 Hs			1 406
+	Hs
		896302 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RING1_HUMAN (1-406): 2.01e-114: 342: 100.00
+	Hs
		919711 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RING1_HUMAN (1-406): 2.01e-114: 342: 100.00
+	Hs
		896360 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		72155 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		896370 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRIM5_HUMAN (39-392): 3.48e-68: 225: 14.85
+	Hs
		72161 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		TRIM5_HUMAN (39-392): 3.48e-68: 225: 14.85
+	Hs
		717650 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Zm
		13425 B4FC97_MAIZE (1-52): 2.27e-30: 106: 38.46		A0A1D6FSN7_MAIZE (22-366): 7.02e-52: 183: 23.86
+	Hs
		896344 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RN138_HUMAN (31-190): 6.27e-46: 160: 18.68
+	Hs
		72148 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		RN138_HUMAN (31-190): 6.27e-46: 160: 18.68
+	Hs
		896362 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		BARD1_HUMAN (4-335): 2.56e-39: 151: 13.35
+	Hs
		919801 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RN138_HUMAN (31-190): 6.27e-46: 160: 18.68
+	Hs
		584923 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RO52_HUMAN (33-392): 4.67e-43: 158: 13.14
+	Hs
		919794 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		COP1_HUMAN (40-326): 3.5e-39: 151: 18.31
+	Hs
		749302 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63
+	Hs
		896381 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRI39_HUMAN (39-392): 2e-35: 138: 13.84
+	Hs
		896366 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRI34_HUMAN (39-392): 1.13e-34: 136: 10.43
+	Hs
		72168 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		TRI39_HUMAN (39-392): 2e-35: 138: 13.84
+	Hs
		72158 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		TRI34_HUMAN (39-392): 1.13e-34: 136: 10.43
+	Hs
		749339 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63