Interactor 1: PGH2 (P35354)
Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)
Gene: PTGS2

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 11971025, 21790943
Identification Methods electrophoretic mobility supershift assay, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0009410 - response to xenobiotic stimulus
GO:0010575 - positive regulation of vascular endothelial growth factor production
GO:0019899 - enzyme binding
GO:0042803 - protein homodimerization activity
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 604
Hs

1 551
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024