Interactor 1: PGH2 (P35354)
Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)
Gene: PTGS2

Interactor 2: PTGIS (Q16647)
Prostacyclin synthase (EC 5.3.99.4) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Prostaglandin I2 synthase)
Gene: PTGIS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 21035466
Identification Methods fluorescent resonance energy transfer
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001516 - prostaglandin biosynthetic process
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005901 - caveola
GO:0019371 - cyclooxygenase pathway
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 604
Hs

1 500
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024