HitPredict - High confidence protein-protein interactions

Interactor 1: NMDE1 (P35436)
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A)
Gene: Grin2a

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007611 - learning or memory GO:0007612 - learning GO:0007613 - memory and 16 others more... GO:0007626 - locomotory behavior GO:0008270 - zinc ion binding GO:0014069 - postsynaptic density GO:0040011 - locomotion GO:0043005 - neuron projection GO:0043197 - dendritic spine GO:0044877 - protein-containing complex binding GO:0045211 - postsynaptic membrane GO:0048167 - regulation of synaptic plasticity GO:0050804 - modulation of chemical synaptic transmission GO:0051968 - positive regulation of synaptic transmission, glutamatergic GO:0060291 - long-term synaptic potentiation GO:0097110 - scaffold protein binding GO:0098978 - glutamatergic synapse GO:0099092 - postsynaptic density, intracellular component GO:2000463 - positive regulation of excitatory postsynaptic potential
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1	1464
Mm

1	1730

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Last updated: 15 Jul 2024