HitPredict

Interactor 1: NMDZ1 (P35438)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Interactor 2: CDKL5 (Q3UTQ8)
Cyclin-dependent kinase-like 5 (EC 2.7.11.22)
Gene: CDKL5

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0098978 - glutamatergic synapse
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 938 Mm			1 938
+	Mm
		620950 GRIA2_MOUSE (3-856): 0: 628: 21.55		CDKL5_MOUSE (1-938): 0: 747: 100.00
+	Mm
		963723 NMDE2_MOUSE (4-938): 0: 628: 23.86		CDKL5_MOUSE (1-938): 0: 747: 100.00
+	Mm
		659444 NMDZ1_MOUSE (1-938): 0: 920: 100.00		KCC2B_MOUSE (3-555): 1.32e-137: 424: 20.46
+	Rn
		514948 GRIA4_RAT (7-888): 0: 661: 21.72		KCC2G_RAT (5-555): 7.53e-136: 418: 20.86
+	Rn
		550161 NMDE2_RAT (4-938): 0: 632: 23.96		KCC2D_RAT (3-559): 3.01e-138: 425: 19.75
+	Mm
		659449 NMDE2_MOUSE (4-938): 0: 628: 23.86		KCC2B_MOUSE (3-555): 1.32e-137: 424: 20.46
+	Hs
		625438 NMDE3_HUMAN (6-924): 0: 601: 22.92		CDK2_HUMAN (10-303): 1.85e-150: 447: 37.16
+	Rn
		550160 NMDE1_RAT (1-923): 0: 594: 24.11		KCC2D_RAT (3-559): 3.01e-138: 425: 19.75