Protein: UB2R2
Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2)

Gene: UB2R2, UBE2R2
Organism: Homo sapiens
Interactions: 129
UniProt ID: Q712K3

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921315

RBX1
E3 ubiquitin-protein ligase RBX1

8

20

Small-scale

0.965

High

475959

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

5

20

Small-scale

0.914

High

1174554

FBW1A
F-box/WD repeat-containing protein 1A

4

20

Small-scale

0.899

High

607099

UBA1
Ubiquitin-like modifier-activating enzyme 1

4

20

Small-scale

0.888

High

1174552

FBW1B
F-box/WD repeat-containing protein 11

3

20

High-throughput

0.847

High

312622

ARI2
E3 ubiquitin-protein ligase ARIH2

1

20

High-throughput

0.698

High

1174502

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

20

High-throughput

0.698

High

1174513

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

16

High-throughput

0.698

High

1174553

CBLC
E3 ubiquitin-protein ligase CBL-C

1

20

High-throughput

0.698

High

1174500

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

15

Small-scale

0.692

High

827962

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

16

High-throughput

0.691

High

863472

COPA
Coatomer subunit alpha

1

3

High-throughput

0.691

High

227854

PRKN
E3 ubiquitin-protein ligase parkin

1

20

Small-scale

0.647

High

962833

MDM2
E3 ubiquitin-protein ligase Mdm2

1

13

Small-scale

0.647

High

1174518

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

20

Small-scale

0.647

High

1174522

RNF31
E3 ubiquitin-protein ligase RNF31

1

20

Small-scale

0.647

High

1174523

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

20

Small-scale

0.647

High

962711

IRF9
Interferon regulatory factor 9

2

2

High-throughput

0.628

High

1174541

BATF3
Basic leucine zipper transcriptional factor ATF-like 3

2

3

High-throughput

0.628

High

1174504

R113B
RING finger protein 113B

1

1

High-throughput

0.625

High

1174517

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.622

High

1174551

HERC5
E3 ISG15--protein ligase HERC5

1

20

Small-scale

0.618

High

837813

MEOX1
Homeobox protein MOX-1

3

5

High-throughput

0.616

High

132912

SDCB1
Syntenin-1

2

3

High-throughput

0.606

High

924329

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

20

High-throughput

0.590

High

725479

COPB2
Coatomer subunit beta'

1

3

High-throughput

0.575

High

924045

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

20

High-throughput

0.575

High

1174525

TEAN2
Transcription elongation factor A N-terminal and central domain-containing protein 2

2

1

High-throughput

0.574

High

180992

GSC2
Homeobox protein goosecoid-2

2

4

High-throughput

0.553

High

902329

COPZ1
Coatomer subunit zeta-1

1

1

High-throughput

0.536

High

1102001

CTC1
CST complex subunit CTC1

1

1

High-throughput

0.536

High

1174549

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.536

High

717180

CTNB1
Catenin beta-1

1

4

Small-scale

0.501

High

1174507

SYT2
Synaptotagmin-2

1

1

High-throughput

0.489

High

1174536

STN1
CST complex subunit STN1

1

1

High-throughput

0.489

High

854803

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.486

High

1174520

PLPL2
Patatin-like phospholipase domain-containing protein 2

1

0

High-throughput

0.486

High

532560

TCTP
Translationally-controlled tumor protein

1

5

High-throughput

0.479

High

882383

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.479

High

1174537

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

0

Small-scale

0.458

High

1174501

MAEA
E3 ubiquitin-protein transferase MAEA

1

6

High-throughput

0.457

High

48397

ESYT2
Extended synaptotagmin-2

1

4

High-throughput

0.445

High

201030

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

1

High-throughput

0.445

High

277081

STAM2
Signal transducing adapter molecule 2

1

6

High-throughput

0.445

High

335456

NB5R3
NADH-cytochrome b5 reductase 3

1

1

High-throughput

0.445

High

432779

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

2

High-throughput

0.445

High

502255

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.445

High

653638

CALR
Calreticulin

1

4

High-throughput

0.445

High

822069

KC1A
Casein kinase I isoform alpha

1

3

High-throughput

0.445

High

827807

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

1

High-throughput

0.445

High

847523

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.445

High

863256

COPB
Coatomer subunit beta

1

1

High-throughput

0.445

High

891198

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

3

High-throughput

0.445

High

1026709

PRDX4
Peroxiredoxin-4

1

1

High-throughput

0.445

High

1174503

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.445

High

1174508

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.445

High

1174510

VP37A
Vacuolar protein sorting-associated protein 37A

1

1

High-throughput

0.445

High

1174514

SCFD1
Sec1 family domain-containing protein 1

1

1

High-throughput

0.445

High

1174524

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.445

High

1174548

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.445

High

1174558

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.445

High

1174538

SP110
Sp110 nuclear body protein

1

8

High-throughput

0.437

High

1174542

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

Small-scale

0.437

High

58101

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.426

High

149667

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.426

High

199348

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.426

High

818963

COPD
Coatomer subunit delta

1

0

High-throughput

0.426

High

945856

NUCB2
Nucleobindin-2

1

0

High-throughput

0.426

High

1065262

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.426

High

1065375

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

1165380

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.426

High

1174521

ASTRA
Protein Aster-A

1

0

High-throughput

0.426

High

1174526

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

1174531

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

1174533

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.426

High

1174534

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

1174557

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

99798

F5H6I7
Atlastin GTPase 3

1

2

High-throughput

0.407

High

258941

RTN2
Reticulon-2

1

2

High-throughput

0.407

High

297760

MICA2
[F-actin]-monooxygenase MICAL2

1

2

High-throughput

0.407

High

307058

RTN3
Reticulon-3

1

2

High-throughput

0.407

High

310692

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.407

High

402179

JUN
Transcription factor Jun

1

2

High-throughput

0.407

High

654465

CALX
Calnexin

1

4

High-throughput

0.407

High

833253

TMEDA
Transmembrane emp24 domain-containing protein 10

1

4

High-throughput

0.407

High

847291

SSRD
Translocon-associated protein subunit delta

1

1

High-throughput

0.407

High

950644

ARF5
ADP-ribosylation factor 5

1

4

High-throughput

0.407

High

1058455

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.407

High

1071783

TMED2
Transmembrane emp24 domain-containing protein 2

1

3

High-throughput

0.407

High

1072909

DHC24
Delta(24)-sterol reductase

1

1

High-throughput

0.407

High

1077661

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

2

High-throughput

0.407

High

1120940

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

3

High-throughput

0.407

High

1174506

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.407

High

1174511

ATLA2
Atlastin-2

1

2

High-throughput

0.407

High

1174515

ATLA1
Atlastin-1

1

2

High-throughput

0.407

High

1174528

ERP44
Endoplasmic reticulum resident protein 44

1

1

High-throughput

0.407

High

1174529

ESYT1
Extended synaptotagmin-1

1

4

High-throughput

0.407

High

1174532

LNP
Endoplasmic reticulum junction formation protein lunapark

1

1

High-throughput

0.407

High

1174535

TMX1
Thioredoxin-related transmembrane protein 1

1

2

High-throughput

0.407

High

1174540

RTN4
Reticulon-4

1

2

High-throughput

0.407

High

1174543

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

High-throughput

0.407

High

1174546

PSD3
PH and SEC7 domain-containing protein 3

1

1

High-throughput

0.407

High

1174547

TECR
Very-long-chain enoyl-CoA reductase

1

1

High-throughput

0.407

High

1174555

DHRS7
Dehydrogenase/reductase SDR family member 7

1

3

High-throughput

0.407

High

1174556

TMED5
Transmembrane emp24 domain-containing protein 5

1

3

High-throughput

0.407

High

1174516

APBP2
Amyloid protein-binding protein 2

1

0

High-throughput

0.299

High

325530

CLIC3
Chloride intracellular channel protein 3

1

0

High-throughput

0.279

Low

1129266

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

0

High-throughput

0.279

Low

1174550

PGAP2
Post-GPI attachment to proteins factor 2

1

0

High-throughput

0.279

Low

1100072

INF2
Inverted formin-2

1

0

High-throughput

0.265

Low

262490

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

986931

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.249

Low

50176

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

202909

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.232

Low

266183

ERLN1
Erlin-1

1

0

High-throughput

0.232

Low

532152

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.232

Low

961705

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.232

Low

1062552

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.232

Low

1070844

RCN1
Reticulocalbin-1

1

0

High-throughput

0.232

Low

1174505

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.232

Low

1174509

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.232

Low

1174512

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.232

Low

1174519

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.232

Low

1174527

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.232

Low

1174530

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.232

Low

1174539

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.232

Low

1174544

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.232

Low

1174545

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024