HitPredict

Interactor 1: NMDZ1 (P35438)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Interactor 2: SRC8 (Q60598)
Src substrate cortactin
Gene: Cttn

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	10862698
Identification Methods	affinity chromatography technology, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005886 - plasma membrane GO:0043197 - dendritic spine GO:0098978 - glutamatergic synapse
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 938 Mm			1 546
+	Mm
		620956 GRIA2_MOUSE (3-856): 0: 628: 21.55		SRC8_MOUSE (1-546): 6.56e-168: 488: 100.00
+	Mm
		963725 NMDE2_MOUSE (4-938): 0: 628: 23.86		SRC8_MOUSE (1-546): 6.56e-168: 488: 100.00
+	Hs
		786734 GRIA2_HUMAN (3-856): 0: 631: 21.55		SRC8_HUMAN (1-546): 6.05e-164: 478: 92.18
+	Hs
		984260 NMDZ1_HUMAN (1-938): 0: 914: 99.04		SPTN1_HUMAN (141-545): 1.96e-38: 153: 15.16
+	Rn
		555251 GRIA4_RAT (7-888): 0: 661: 21.72		SPTN1_RAT (141-545): 3.46e-38: 152: 14.03
+	Hs
		1028137 NMDE2_HUMAN (4-938): 0: 634: 24.07		SPTN1_HUMAN (141-545): 1.96e-38: 153: 15.16
+	Hs
		786733 GRIA2_HUMAN (3-856): 0: 631: 21.55		SPTN1_HUMAN (141-545): 1.96e-38: 153: 15.16
+	Hs
		1018891 NMDE1_HUMAN (1-923): 0: 623: 24.11		SPTN1_HUMAN (141-545): 1.96e-38: 153: 15.16
+	Hs
		1059973 NMDE3_HUMAN (6-924): 0: 601: 22.92		LASP1_HUMAN (302-545): 2.98e-38: 143: 20.88
+	Hs
		1060503 NMDE3_HUMAN (6-924): 0: 601: 22.92		DBNL_HUMAN (249-546): 3.9e-34: 135: 22.86